1.06576

di-Sodium hydrogen phosphate dihydrate

EMPROVE^® ESSENTIAL, Ph. Eur., BP, USP

• Synonym(s): Sodium phosphate dibasic dihydrate, Sodium monohydrogen phosphate, Sodium phosphate dibasic, sec-Sodium phosphate, Disodium hydrogen phosphate dihydrate, Disodium phosphate, di-Sodium hydrogen phosphate dihydrate
• Linear Formula: Na₂HPO₄ · 2H₂O
• CAS Number: 10028-24-7
• Molecular Weight: 177.99
• MDL number: MFCD00149182
• EC Index Number: 231-448-7

Properties

• Agency: BP; Ph. Eur.; USP
• Quality Level: 500
• product line: EMPROVE^® ESSENTIAL
• form: solid
• pH: 9.0-9.4 (20 °C, 50 g/L in H₂O)
• mp: 92.5 °C (Elimination of water of crystallisation)
• solubility: 93 g/L
• density: 2.1 g/cm³ at 20 °C
• application(s): liquid formulation; ophthalmics; pharmaceutical; semi-solid formulation; solid formulation
• storage temp.: 2-30°C
• SMILES string: O.O.[Na+].[Na+].OP([O-])([O-])=O
• InChI: 1S/2Na.H3O4P.2H2O/c;;1-5(2,3)4;;/h;;(H3,1,2,3,4);2*1H2/q2*+1;;;/p-2
• InChI key: KDQPSPMLNJTZAL-UHFFFAOYSA-L

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

di-Sodium hydrogen phosphate dihydrate is typically used as a phosphate buffer system component for biomolecule downstream chromatography steps or final liquid formulation.

Packaging

1, 5 kg in PE bottle

12 kg in PE bag (in PE pail)

25 kg in PE bag (in PE square drum)

25 kg in double PE bag (DPES in carton)

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable