Accurate protein binding affinities were measured using bioSPME more rapidly than membrane dialysis (RED) techniques. Binding affinities correlated to the reference values.
SPME is used in the analysis of amphetamine compounds by doing pre-extraction derivatization, and is also used in general determinations of other drugs of abuse.
Bisphenol A (BPA) plastic is controversial in food and beverage containers. This study demonstrates SPME of BPA from an energy drink using an overcoated PDMS/DVB fiber, followed by GC/MS/MS analysis using SLB-PAHms GC Column.
In the flavor and fragrance industry, analytical chemists are often required to isolate key ingredients, off-flavor components, or trace organic compounds from their sample matrices without altering their structure or composition.
SPME fibers with Carboxen®/Polydimethylsiloxane (CAR/PDMS) and Polydimethylsiloxane/ Divinylbenzene (PDMS/DVB) coatings are now available on a nitinol core (NIT) in a SS assembly for improved fiber performance.
A comparison between Carboxen®/PDMS coated nitinol core and fused silica core adsorbent SPME fibers for factors, such as coating process, testing process, inertness, raw materials, and durability.
Comparative analysis of Supel™ BioSPME 96-Pin device with a rapid equilibrium dialysis technique for accuracy of measured values, sample cleanliness, and workflow time in drug protein binding.