All Photos(2)

850375C

Avanti

18:1 (Δ9-Cis) PC (DOPC)

1,2-dioleoyl-sn-glycero-3-phosphocholine, chloroform

Synonym(s):
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine; DOPC; PC(18:1(9Z)/18:1(9Z))
Empirical Formula (Hill Notation):
C44H84NO8P
CAS Number:
Molecular Weight:
786.11
NACRES:
NA.25

assay

>99% (TLC)

packaging

pkg of 1 × 2.5 mL (850375C-25mg)
pkg of 2 × 20 mL (850375C-1g)
pkg of 2 × 4 mL (850375C-200mg)
pkg of 5 × 4 mL (850375C-500mg)

concentration

10 mg/mL (850375C-25mg)
25 mg/mL (850375C-1g)
25 mg/mL (850375C-200mg)
25 mg/mL (850375C-500mg)

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C44H84NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h20-23,42H,6-19,24-41H2,1-5H3/b22-20-,23-21-/t42-/m0/s1

InChI key

SNKAWJBJQDLSFF-AOMFJDGTSA-N

General description

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

18:1 (Δ9-Cis) PC (DOPC) has been used in the preparation of planar supported lipid bilayer for fluorescence microscopy. It is also suitable for use in the preparation of protocells.

Biochem/physiol Actions

18:1 (Δ9-Cis) PC (DOPC) shows high resistance to the toxic effects of dimethyl sulfoxide (DMSO).

Packaging

5 mL Clear Glass Sealed Ampule (850375C-200mg)
5 mL Clear Glass Sealed Ampule (850375C-25mg)
5 mL Clear Glass Sealed Ampule (850375C-500mg)
30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850375C-1g)

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Mesoporous silica-supported lipid bilayers (protocells) for DNA cargo delivery to the spinal cord
Dengler EC, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 168(2), 209-224 (2013)
Molecular dynamics simulations of the interactions of DMSO with DPPC and DOPC phospholipid membranes
Hughes ZE, et al.
The Journal of Physical Chemistry B, 116(39), 11911-11923 (2012)
K-Ras4B remains monomeric on membranes over a wide range of surface densities and lipid compositions
Chung JK, et al.
Biophysical Journal, 114(1), 137-145 (2018)
Yachong Guo et al.
ACS nano (2018-11-20)
Increasing awareness of bioeffects and toxicity of nanomaterials interacting with cells puts in focus the mechanisms by which nanomaterials can cross lipid membranes. Apart from well-discussed energy-dependent endocytosis for large objects and passive diffusion through membranes by solute molecules, other...
Liulin Wang et al.
Langmuir : the ACS journal of surfaces and colloids, 34(36), 10764-10773 (2018-07-28)
Monoamine oxidase A and B (MAO-A and B) are mitochondrial outer membrane enzymes that are implicated in a number of human diseases, and the pharmacological inhibition of these enzymes is a promising therapeutic strategy to alleviate disease symptoms. It has...

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