If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 L | Estimated to ship onApril 13, 2026fromMerck Chemicals and LS SA | €64.30 | |
| 2.5 L | Estimated to ship onApril 13, 2026fromMerck Chemicals and LS SA | €133.00 | |
| 4 L | Estimated to ship onApril 13, 2026fromMerck Chemicals and LS SA | €177.00 | |
| 185 L | Available to ship TODAYfromMerck Chemicals and LS SA | €7,300.00 |
About This Item
Product Name
Methanol, hypergrade for LC-MS LiChrosolv®
Quality Level
agency
suitable for ASTM® 7968, suitable for ASTM® 7979, suitable for DIN 38407-42, suitable for EPA 1621, suitable for EPA 1633, suitable for EPA 533, suitable for EPA 537.1, suitable for EPA 8327, suitable for EPA ACB B21-02, suitable for EPA ACB B23-05b, suitable for EPA OTM-45, suitable for GB 31604.35-2016, suitable for GB 5009.253-2016, suitable for ISO 21675 2019, suitable for ISO 25101, suitable for ISO/CEN 15968-2010
reg. compliance
suitable for FDA C-010.02
vapor density
1.11 (vs air)
vapor pressure
128 hPa ( 20 °C), 410 mmHg ( 50 °C), 97.68 mmHg ( 20 °C)
product line
LiChrosolv®
assay
≥99.9% (GC)
form
liquid
autoignition temp.
725 °F
potency
5628 mg/kg LD50, oral (Rat), 17100 mg/kg LD50, skin (Rabbit)
expl. lim.
36 %
technique(s)
HPLC: suitable, LC/MS: suitable
SMILES string
CO
impurities
≤0.0002 meq/g Acidity, ≤0.0002 meq/g Alkalinity, ≤0.01% Water, ≤10 ppb Al (Aluminium), ≤10 ppb Ca (Calcium), ≤10 ppb Fe (Iron), ≤10 ppb Mg (Magnesium), ≤100 ppb Na (Sodium), ≤5 ppb Any further metal (ICP-MS), ≤5 ppb K (Potassium)
evapn. residue
≤1.0 mg/L
transmittance
210 nm, ≥35%, 220 nm, ≥60%, 230 nm, ≥75%, 260 nm, ≥98%
refractive index
n20/D 1.329 (lit.)
kinematic viscosity
0.54-0.59 cSt(20 °C)
bp
64.7 °C (lit.)
mp
−98 °C (lit.)
transition temp
flash point 9.7 °C
density
0.791 g/mL at 25 °C (lit.)
application(s)
PFAS testing
format
neat
storage temp.
2-30°C
InChI
1S/CH4O/c1-2/h2H,1H3
InChI key
OKKJLVBELUTLKV-UHFFFAOYSA-N
General description
Application
- The composition of chemicals and anti-osteogenic properties in the volatile extracts from Homalomena gigantea rhizome: This study highlights methanol′s role in the extraction and analysis of volatile organic compounds from medicinal plants, providing insights valuable for researchers in pharmacology and natural product chemistry (Thanh et al., 2024).
- A homochiral tartrate-bridged dinuclear chromium(III) complex anion with a resonance-assisted hydrogen bond for proton conduction: Methanol is used as a solvent in the synthesis of complex inorganic compounds, which are essential in developing new materials for energy applications, such as proton exchange membranes (Dunatov et al., 2024).
Preparation Note
Analysis Note
Identity (IR): conforms
Evaporation residue: ≤ 1.0 mg/l
Water: ≤ 0.01 %
Acidity: ≤ 0.0002 meq/g
Alkalinity: ≤ 0.0002 meq/g
Al (Aluminium): ≤ 10 ppb
Ca (Calcium): ≤ 10 ppb
Fe (Iron): ≤ 10 ppb
K (Potassium): ≤ 5 ppb
Mg (Magnesium): ≤ 10 ppb
Na (Sodium): ≤ 100 ppb
Any further metal (ICP-MS): ≤ 5 ppb
Gradient grade (at 220 nm): ≤ 2.0 mAU
Gradient grade (at 235 nm): ≤ 1.0 mAU
Fluorescence (as quinine at 254 nm): ≤ 1.0 ppb
Fluorescence (as quinine at 365 nm): ≤ 0.5 ppb
Transmission (at 210 nm): ≥ 35 %
Transmission (at 220 nm): ≥ 60 %
Transmission (at 230 nm): ≥ 75 %
Transmission (from 260 nm): ≥ 98 %
Suitable for LC-MS; Intensity of background mass peak based on reserpine(APCI/ESI positive): ≤ 2 ppb
Suitable for LC-MS; Intensity of background mass peak based on reserpine(APCI/ESI negative): ≤ 20 ppb
Filtered by 0.2 µm filter.
Other Notes
Legal Information
1 of 1
This Item | |||
|---|---|---|---|
| application(s) PFAS testing | application(s) PFAS testing | application(s) PFAS testing | application(s) PFAS testing |
| Quality Level 100 | Quality Level 200 | Quality Level 100 | Quality Level 200 |
| assay ≥99.9% (GC) | assay 99.9% (GC) | assay ≥99.9% | assay ≥99.9% (GC) |
| technique(s) HPLC: suitable, LC/MS: suitable | technique(s) HPLC: suitable, LC/MS: suitable, UHPLC: suitable | technique(s) HPLC: suitable | technique(s) - |
| form liquid | form liquid | form liquid | form liquid |
| autoignition temp. 725 °F | autoignition temp. 725 °F | autoignition temp. 725 °F | autoignition temp. 725 °F |
Still not finding the right product?
Explore all of our products under Methanol
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes,Central nervous system
Storage Class
3 - Flammable liquids
flash_point_f
49.5 °F - closed cup
flash_point_c
9.7 °C - closed cup
Regulatory Listings
Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.
67-56-1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Protocols
Separation of various acids and compounds by molecular weight: PAA, PEI, PIDADMACl, PAS, cationic dextran, chitosan
Separation of Pyridoxine Hydrochloride (B6), analytical standard; Thiamine Hydrochloride (B1), analytical standard
Articles
An overview of nitrosamine impurity testing, worldwide regulations, and key considerations in filter selection for sample preparation and analysis.
For use as a marker in SDS-PAGE; Albumin from chicken egg white, For use as a marker in SDS-PAGE; L-Lactic Dehydrogenase from rabbit muscle, Type XI, lyophilized powder, 600-1,200 units/mg protein
In this article we provide a complete workflow of quantification and identification of acylcarnitines in dried blood spots (DBS) using stable isotope-labeled (SIL) acylcarnitines CRMs by FIA-MS/MS.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 1060354000 | 04054839365409 |
| 1060359185 | 04027269059552 |
| 1060359910 | 04027269059569 |
-
How can I determine the shelf life / expiration / retest date of this product?
1 answer-
Helpful?
-
-
Assay details not mentioned for hypergrade lcms methanol and acetonitrile on the solvent bottles
1 answer-
Assay details for both hypergrade LC-MS methanol and acetonitrile are available in the Certificate of Analysis.
Helpful?
-
-
How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
Helpful?
-



