Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
436143
Sodium dodecyl sulfate
ACS reagent, ≥99.0%
Synonym(s):
Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate
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grade
ACS reagent
Quality Level
description
anionic
62
Assay
≥99.0%
form
solid
mol wt
288.38 g/mol
impurities
≤0.06 meq/g Titr. Base
≥96.0% fatty alcohols
<4.0% unsulfated alcohols
loss
≤1.0% loss on drying
mp
204-207 °C (lit.)
solubility
H2O: soluble 1 gm in 10 ml (opalescent solution)
density
1.03 g/cm3 at 20 °C
cation traces
heavy metals (as Pb): ≤0.002%
λ
3 %H2O reference
UV absorption
λ: 220-350 nm Amax: ≤0.1
HLB
40
SMILES string
[Na+].CCCCCCCCCCCCOS([O-])(=O)=O
InChI
1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1
InChI key
DBMJMQXJHONAFJ-UHFFFAOYSA-M
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This Item | L3771 | 75746 | 62862 |
|---|---|---|---|
| grade ACS reagent | grade for molecular biology | grade - | grade - |
| form solid | form powder | form rod | form - |
| assay ≥99.0% | assay ≥98.5% (GC) | assay ≥99.0% (GC) | assay ≥90% ((Assay)) |
| description anionic, 62 | description anionic | description anionic | description anionic, 62 |
| solubility H2O: soluble 1 gm in 10 ml (opalescent solution) | solubility water: soluble | solubility H2O: soluble 0.29 gm in 10ml, clear, colorless, H2O: 0.1 M at 20 °C, clear, colorless, 130 g/L at 20 °C (68 °F) | solubility water: soluble |
| mp 204-207 °C (lit.) | mp 204-207 °C (lit.) | mp 204 - 207 °C (399 - 405 °F), 204-207 °C (lit.) | mp 204-207 °C (lit.) |
General description
In protein biochemistry, SDS plays a pivotal role in protein extraction and SDS-PAGE (sodium dodecyl sulfate-polyacrylamide gel electrophoresis). Its ability to denature proteins by disrupting their secondary and tertiary structures allows for their uniform migration through a polyacrylamide gel matrix based on their molecular weight. This technique, SDS-PAGE, has become an indispensable tool for analyzing protein size and purity.
Beyond protein analysis, SDS also finds applications in nucleic acid extraction and hybridization techniques. Its detergent properties aid in the lysis of cells and the solubilization of cellular components, facilitating the extraction of DNA and RNA. This makes SDS a valuable reagent in various molecular biology protocols, including PCR (polymerase chain reaction) and Southern blotting. Sodium dodecyl sulfate stands as a versatile and widely used surfactant with a diverse range of applications due to its ability to solubilize, denature, and separate biological molecules for cell biology and biochemical research.
Application
Biochem/physiol Actions
Features and Benefits
- Highly versatile surfactant for your molecular biology and biochemical research
- Tested to confirm low levels of heavy metal contamination, ensuring suitability for various applications
Other Notes
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
4.1B - Flammable solid hazardous materials
WGK
WGK 2
Flash Point(F)
338.0 °F
Flash Point(C)
170 °C
Personal Protective Equipment
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If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdfHelpful?
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