Phenylboronic acid (PBA) is an organoboronic acid. It behaves as a molecular receptor that can attach to compounds containing cis-diol group. Microwave-assisted Suzuki coupling of aryl chlorides with phenylboronic acid in the presence of Pd/C (catalyst) and water (solvent) has been described. Palladium-catalyzed cross-coupling reaction of phenylboronicacid with haloarenes to afford biaryls has been reported.
Phenylboronic acid may be employed in the following reactions:
Rhodium-catalyzed intramolecular amination.
Pd-catalyzed direct arylation.
Mizoroki-Heck and Suzuki-Miyaura coupling reactions catalyzed by palladium nanoparticles.