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H8000

Sigma-Aldrich

L-Histidine

ReagentPlus®, ≥99% (TLC)

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Synonym(s):
(S)-2-Amino-3-(4-imidazolyl)propionic acid, NSC 137773
Empirical Formula (Hill Notation):
C6H9N3O2
CAS Number:
Molecular Weight:
155.15
Beilstein:
84088
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

Quality Level

product line

ReagentPlus®

Assay

≥99% (TLC)

form

powder

color

white to off-white

mp

282 °C (dec.) (lit.)

solubility

0.5 M HCl: 50 mg/mL

application(s)

cell analysis

SMILES string

N[C@@H](Cc1c[nH]cn1)C(O)=O

InChI

1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1

InChI key

HNDVDQJCIGZPNO-YFKPBYRVSA-N

Gene Information

human ... CA1(759) , CA2(760)

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1 of 4

This Item
53319H6034PHR1108
L-Histidine ReagentPlus®, ≥99% (TLC)

H8000

L-Histidine

-
L-Histidine BioUltra, ≥99.5% (NT)

53319

L-Histidine

Premium Grade
L-Histidine suitable for cell culture, meets EP, USP testing specifications, from non-animal source

H6034

L-Histidine

-
L-Histidine Pharmaceutical Secondary Standard; Certified Reference Material

PHR1108

L-Histidine

-
assay

≥99% (TLC)

assay

≥99.5% (NT)

assay

98.5-101.0%

assay

-

product line

ReagentPlus®

product line

BioUltra

product line

-

product line

-

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

300

solubility

0.5 M HCl: 50 mg/mL

solubility

H2O: 0.1 M at 20 °C, clear, colorless

solubility

H2O: 50 mg/mL

solubility

-

mp

282 °C (dec.) (lit.)

mp

282 °C (dec.) (lit.), ~285 °C (dec.)

mp

282 °C (dec.) (lit.)

mp

282 °C (dec.) (lit.)

Application

L-histidine has been used for the selection of transformed cells. It has also been used to study its effects on the formation of verteporfin cross-linked oligomers in cellular homogenates.

Biochem/physiol Actions

L-Histidine is an essential amino acid. It binds to metal ions and may aid in the transport of copper. Histidine is widely present at the active sites of enzymes. It also has a role in binding of heme groups, macromolecules and phosphate groups in the binding sites of proteins.
Precursor of histamine by action of histidine decarboxylase.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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application for HPLC

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