H8000

L-Histidine

ReagentPlus^®, ≥99% (TLC)

• Synonym(s): (S)-2-Amino-3-(4-imidazolyl)propionic acid, NSC 137773
• Empirical Formula (Hill Notation): C₆H₉N₃O₂
• CAS Number: 71-00-1
• Molecular Weight: 155.15
• Beilstein: 84088
• EC Number: 200-745-3
• MDL number: MFCD00064315
• eCl@ss: 32160406
• PubChem Substance ID: 24895816
• NACRES: NA.26

Properties

• Quality Level: 200
• product line: ReagentPlus^®
• Assay: ≥99% (TLC)
• form: powder
• color: white to off-white
• mp: 282 °C (dec.) (lit.)
• solubility: 0.5 M HCl: 50 mg/mL
• application(s): cell analysis
• SMILES string: N[C@@H](Cc1c[nH]cn1)C(O)=O
• InChI: 1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1
• InChI key: HNDVDQJCIGZPNO-YFKPBYRVSA-N
• Gene Information: human ... CA1(759) , CA2(760)

Description

Application

L-histidine has been used for the selection of transformed cells. It has also been used to study its effects on the formation of verteporfin cross-linked oligomers in cellular homogenates.

Biochem/physiol Actions

L-Histidine is an essential amino acid. It binds to metal ions and may aid in the transport of copper. Histidine is widely present at the active sites of enzymes. It also has a role in binding of heme groups, macromolecules and phosphate groups in the binding sites of proteins.

Precursor of histamine by action of histidine decarboxylase.

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves