Merck
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L4509

Sigma-Aldrich

Sodium dodecyl sulfate

ReagentPlus®, ≥98.5% (GC)

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Synonym(s):
Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate
Linear Formula:
CH3(CH2)11OSO3Na
CAS Number:
Molecular Weight:
288.38
Beilstein:
3599286
EC Number:
MDL number:
eCl@ss:
39093306
PubChem Substance ID:
NACRES:
NA.21

biological source

synthetic

Quality Level

description

anionic

product line

ReagentPlus®

Assay

≥98.5% (GC)

form

powder

mol wt

micellar avg mol wt 18,000

aggregation number

62

impurities

<2.0% water (Karl Fischer)

CMC

7-10 mM (20-25°C)

mp

204-207 °C (lit.)

transition temp

cloud point >100 °C

solubility

water: soluble

density

0.425 g/cm3

cation traces

Na: 7.0-9.0%

HLB

40

SMILES string

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

InChI key

DBMJMQXJHONAFJ-UHFFFAOYSA-M

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This Item
L60268.2205071726
Sodium dodecyl sulfate ReagentPlus&#174;, &#8805;98.5% (GC)

Sigma-Aldrich

L4509

Sodium dodecyl sulfate

-
Sodium dodecyl sulfate BioXtra, &#8805;99.0% (GC)

Sigma-Aldrich

L6026

Sodium dodecyl sulfate

Premium Grade
Sodium dodecyl sulfate for synthesis

Sigma-Aldrich

8.22050

Sodium dodecyl sulfate

-
Sodium dodecyl sulfate suitable for ion pair chromatography, LiChropur&#8482;, &#8805;99.0%

Supelco

71726

Sodium dodecyl sulfate

-
description

anionic

description

anionic

description

-

description

anionic, 62

product line

ReagentPlus®

product line

BioXtra

product line

-

product line

-

assay

≥98.5% (GC)

assay

≥99.0% (GC)

assay

-

assay

≥99.0% (GC)

form

powder

form

powder

form

powder

form

rod

mol wt

micellar avg mol wt 18,000

mol wt

micellar avg mol wt 18,000

mol wt

-

mol wt

288.38 g/mol

General description

Sodium dodecyl sulfate (SDS), or sodium lauryl sulfate, is widely recognized as an anionic surfactant within the organosulfate class of organic compounds. Its effectiveness as a detergent spans both ionic and anionic conditions. SDS plays a critical role as a protein denaturant, facilitating the solubilization and denaturation of proteins in procedures like protein extraction and SDS-PAGE. Its significance in the electrophoretic separation of proteins and lipids establishes its indispensability for the examination of these molecules in diverse biological experiments. In conclusion, Sodium dodecyl sulfate proves to be an indispensable element in the exploration of biological molecules within the realms of biochemical and cell biology research.

Application

Sodium dodecyl sulphate (SDS) has been used:
  • in the characterization of Enterobacteriaceae strain based on sensitivity to selective compounds
  • to treat human skin in vitro and in vivo to evaluate the role of nuclear localization of 27-kDa heat shock protein (HSP27) in potential skin irritation
  • in the decellularization of porcine heart valve tissue
  • to treat sperm for in vitro induction of sperm decondensation

Anionic detergent

Biochem/physiol Actions

Sodium dodecyl sulphate (SDS) helps to quickly disrupt the biological membranes. It is usually used as one of the major constituent of several reagents, that are used to purify nucleic acids. SDS can block the activity of RNase and deoxyribonuclease (DNase).

Features and Benefits

  • Suitable for Cell Biology and Biochemical Research
  • High purity chemical suitable for multiple research applications

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

4.1B - Flammable solid hazardous materials

WGK

WGK 2

Flash Point(F)

338.0 °F

Flash Point(C)

170 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Resilient ribonucleases
RNA Methodologies: A Laboratory Guide for Isolation and Characterization, 32-45 (1993)
Utility of light scatter in the morphological analysis of sperm
Zucker RM, et al.
Cytometry, 39-47 (1992)
Induction of HSP27 nuclear immunoreactivity during stress is modulated by vitamin C
Boxman ILA, et al.
Experimental Dermatology, 11(6), 509-517 (2002)
Sub-Micellar Concentration of Sodium Dodecyl Sulphate Prevents Thermal Denaturation Induced Aggregation of Plant Lectin, Jacalin
Lavanya V, et al
The Protein Journal, 36(1), 17-27 (2017)
A rapid and reliable alternative to ISO 21528-1: 2004 for detection of Enterobacteriaceae
Joosten H, et al.
International Journal of Food Microbiology, 125(3), 344-346 (2008)

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