Merck
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ED4SS

Sigma-Aldrich

Ethylenediaminetetraacetic acid tetrasodium salt dihydrate

99.0-102.0% (titration)

All Photos(4)
Synonym(s):
EDTA tetrasodium salt, Edathamil, Tetrasodium ethylenediaminetetraacetate dihydrate
Linear Formula:
(NaOOCCH2)2NCH2CH2N(CH2COONa)2 · 2H2O
CAS Number:
10378-23-1
Molecular Weight:
416.20
Beilstein:
3861753
EC Number:
200-573-9
MDL number:
MFCD00150026
PubChem Substance ID:
24894711
NACRES:
NA.77

Quality Level

200

assay

99.0-102.0% (titration)

solubility

H2O: soluble, clear, colorless

SMILES string

O.O.[Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O

InChI

1S/C10H16N2O8.4Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;;;2*1H2/q;4*+1;;/p-4

InChI key

KSYNLCYTMRMCGG-UHFFFAOYSA-J

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Packaging

2.5 kg in poly drum
1 kg in poly bottle
100, 500 g in poly bottle

Application

Used to eliminate enzyme inhibition by traces of heavy metals, and to inhibit enzymes that require divalent cations as cofactors.

Signal Word

Danger

Hazard Statements

H302 + H332 - H318 - H373

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - STOT RE 2

Target Organs

Respiratory Tract

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Product Information Sheet

Product Information Sheet - ED4SS

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Macroautophagy/autophagy, a fundamental process for degradation of macromolecules and organelles, occurs constitutively at a basal level and is upregulated in response to stress. Whether autophagy regulates protein acetylation and microtubule stability in vascular smooth muscle cells (VSMCs) migration, however, remains
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