D9760

L-(−)-Dithiothreitol

≥95%

• Synonym(s): (−)-Cleland’s Reagent, (2R,3R)-1,4-Dimercapto-2,3-butanediol, L-DTT, Cleland reagent chiral
• Empirical Formula (Hill Notation): C₄H₁₀O₂S₂
• CAS Number: 16096-97-2
• Molecular Weight: 154.25
• Beilstein: 2036371
• EC Number: 240-263-0
• MDL number: MFCD00064305
• PubChem Substance ID: 24894326
• NACRES: NA.25

Properties

• Quality Level: 100
• assay: ≥95%
• form: powder
• solubility: H₂O: 50 mg/mL, clear to hazy, colorless
• storage temp.: −20°C
• SMILES string: O[C@@H](CS)[C@@H](O)CS
• InChI: 1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m0/s1
• InChI key: VHJLVAABSRFDPM-IMJSIDKUSA-N

Description

Application

L-DTT [(2R,3R)-1,4-dimercapto-2,3-butanediol; L-dithiothreitol], a chiral bidentate dithiol with two stereogenic centers, may be used in chiroptical response research. L-DDT is proposed as a stereoselective reducing agent for disulfide bridges in complex molecules.

Packaging

100, 500 mg in glass bottle

1 g in glass bottle

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302 - H412
• Precautionary Statements: P273 - P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): 230.0 °F - closed cup
• Flash Point(C): 110 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves