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700087P

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Sex Hormones in Neurodegenerative Processes and Diseases (2018)
25-Hydroxycholesterol: a new life in immunology
McDonald JG and Russell DW
Journal of Leukocyte Biology, 88(6), 1071-1072 (2010)
25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages
Shibata N, et al.
The Journal of biological chemistry, 288(50), 35812-35823 (2013)
Sayali Upasham et al.
The Analyst, 145(3), 784-796 (2019-12-24)
Chronobiology is defined as the temporal fluctuations occurring in the human physiology due to the circadian cycle. These fluctuations are good indicators of the functioning of the Hypothalamic-Pituitary-Adrenal axis (HPA axis) and can be tracked by using biomarkers: cortisol and
Marco Racchi et al.
CNS drug reviews, 9(1), 21-40 (2003-02-22)
The physiological role of dehydroepiandrosterone (DHEA) and its sulphated ester DHEA(S) has been studied for nearly 2 decades and still eludes final clarification. The major interest in DHEA derives from its unique pattern of activity. Its levels exhibit a dramatic
Joseph S Dillon
Current drug targets. Inflammation and allergy, 4(3), 377-385 (2005-08-17)
Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) are metabolic intermediates in the production of potent androgens, estrogens and other less well-characterized steroids. DHEA(S) and closely related steroid hormones have a variety of immunological effects both in vitro and in vivo in
P Ebeling et al.
Lancet (London, England), 343(8911), 1479-1481 (1994-06-11)
Dehydroepiandrosterone (DHEA), with its sulphate conjugate (DHEAS), is the most abundant steroid hormone in the circulation but its physiological importance is unclear. We propose that DHEA has either oestrogen-like or androgen-like effects depending on the hormonal milieu. In premenopausal women
Kuei-Fang Chung et al.
Molecular and cellular endocrinology, 336(1-2), 141-148 (2010-12-07)
Dehydroepiandrosterone producing adrenocortical zona reticularis and the adrenal medulla are in direct contact and are highly intermingled in many species. This results in potentially strong paracrine influences of high local dehydroepiandrosterone concentrations on the adrenal medulla. Dehydroepiandrosterone has neuroprotective properties
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