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Wenjiao Wang et al.
Plant molecular biology, 87(3), 219-233 (2014-12-30)
Most land plants have a wax layer which covers their aerial parts to protect them from environmental stresses, such as drought, UV radiation, and pathogenic invasion. The wax biosynthesis has been well studied previously in Arabidopsis, but it still remains
Ksenia Astafyeva et al.
Langmuir : the ACS journal of surfaces and colloids, 31(24), 6791-6796 (2015-06-03)
The stability of model surfactant bilayers from the poly(ethylene glycol) mono-n-dodecyl ether (C12Ej) family was probed. The surfactant bilayers were formed by the adhesion of emulsion droplets. We generated C12Ej bilayers by forming water-in-oil (w/o) emulsions with saline water droplets
Diren Beyoğlu et al.
Journal of lipid research, 55(11), 2309-2319 (2014-09-07)
A lipidomic and metabolomic investigation of serum and liver from mice was performed to gain insight into the tumor suppressor gene Hint1. A major reprogramming of lipid homeostasis was found in both serum and liver of Hint1-null (Hint(-/-)) mice, with
Joong-Seok Min et al.
Lipids in health and disease, 14, 77-77 (2015-07-24)
Cholesterol oxidation products (COPs) are produced during thermal processing of animal origin foods and are considered to have negative health impacts. The model systems are helpful to understand the impact of various factors on oxidation changes in foods during cooking
Use of organosilicon reagents as protective groups in organic synthesis.
Lalonde M & Chan TH.
Synthesis, 1985(09), 817-845 (1985)
Urszula Czyżewska et al.
Journal of medicinal food, 18(5), 584-591 (2014-09-10)
Propolis is a resin that is collected by honeybees from various plant sources. Due to its pharmacological properties, it is used in commercial production of nutritional supplements in pharmaceutical industry. In this study, gas chromatography-mass spectrometry was applied for quality
Ning Chen et al.
Cytotechnology, 66(6), 945-966 (2013-12-03)
Optimization of cell culture processes can benefit from the systematic analysis of experimental data and their organization in mathematical models, which can be used to decipher the effect of individual process variables on multiple outputs of interest. Towards this goal
M Kosová et al.
Journal of clinical pharmacy and therapeutics, 40(4), 436-440 (2015-05-28)
Parabens have been commonly used as preservatives in pharmaceutical and cosmetics industries for almost 50 years. These compounds are thermostable, pH-stable and inexpensive and have a wide antimicrobial effect. The antimicrobial activity of parabens in emulsion system is limited by
Sarah Thomas et al.
Methods in molecular biology (Clifton, N.J.), 603, 297-305 (2010-01-16)
Indomethacin is a non-narcotic and non-steroidal anti-inflammatory drug used in the treatment of various inflammatory diseases such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. In neonates, it is also used for induction of closure of patent ductus arteriosus (PDA). Its
Saša Petriček et al.
Acta chimica Slovenica, 62(2), 354-361 (2015-06-19)
A mononuclear molecular complex fac-[VCl3(diglyme)] (1) resulted from the reaction of VCl3 and diglyme (diglyme = di(2-methoxyethyl)ether) in dichloromethane. The violet complex 1 is a sensitive substance which slowly oxidized to a new, blue mononuclear molecular complex, fac-[VOCl2(diglyme)] (2) in
Miles Trupp et al.
Journal of Parkinson's disease, 4(3), 549-560 (2014-06-15)
Parkinson's disease (PD) is a progressive, multi-focal neurodegenerative disease for which there is no effective disease modifying treatment. A critical requirement for designing successful clinical trials is the development of robust and reproducible biomarkers identifying PD in preclinical stages. To
Jie Shen et al.
Scientific reports, 5, 8651-8651 (2015-03-04)
It is technically challenging to investigate the function of secreted protein in real time by supply of conditioned medium that contains secreted protein of interest. The internalization of anthrax toxin is facilitated by a secreted protein Dickkopf-1 (DKK1) and its
Jun-ichi Ito et al.
Inorganic chemistry, 47(9), 3763-3771 (2008-03-19)
The reaction of trithiomolybdate [PPh 4] 2[MoOS 3] ( 1) with 2 equiv of trimethylchlorosilane generated trithio-chloro molybdate [PPh 4][MoClS 3] ( 2) in high yield, by way of a siloxy complex [PPh 4][Mo(OSiMe 3)S 3] ( 3). This intriguing
J Hadrévi et al.
Scientific reports, 5, 15925-15925 (2015-11-03)
Chronic musculoskeletal pain exists either as localised to a single region or as widespread to multiple sites in several quadrants of the body. Prospective studies indicate that widespread pain could act as a far end of a continuum of musculoskeletal
Kejun Zhou et al.
Journal of proteome research, 14(6), 2569-2574 (2015-04-23)
Biliary atresia (BA) is a rare neonatal cholestatic disorder caused by obstruction of extra- and intra-hepatic bile ducts. If untreated, progressive liver cirrhosis will lead to death within 2 years. Early diagnosis and operation improve the outcome significantly. Infants with
Devin H Currie et al.
BMC systems biology, 9, 30-30 (2015-06-27)
Thermoanaerobacterium saccharolyticum is a hemicellulose-degrading thermophilic anaerobe that was previously engineered to produce ethanol at high yield. A major project was undertaken to develop this organism into an industrial biocatalyst, but the lack of genome information and resources were recognized
Yeon Jong Koo et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 863(1), 80-87 (2008-02-08)
We developed a quantitative method for the determination of methyl esterase activity, analyzing substrate specificity against three major signal molecules, jasmonic acid methyl ester (MeJA), salicylic acid methyl ester (MeSA), and indole-3-acetic acid methyl ester (MeIAA). We used a silylation
Hongyun Li et al.
Neurobiology of aging, 36(5), 1820-1833 (2015-03-19)
Apolipoprotein D (apoD) is expressed in the brain and levels are increased in affected brain regions in Alzheimer's disease (AD). The role that apoD may play in regulating AD pathology has not been addressed. Here, we crossed both apoD-null mice
Hanne Roberg-Larsen et al.
Steroids, 99(Pt B), 125-130 (2015-02-11)
Due to their non-charged character, liquid chromatography-electrospray ionization-mass spectrometry (LC-ESI-MS) measurements of oxysterols are often performed after derivatization with e.g. charged Girard reagents. However, derivatization reactions are time-consuming and may require numerous steps to remove excess reagent. In addition, extensive
Gati Krushna Panigrahi et al.
Chemical research in toxicology, 28(6), 1120-1132 (2015-04-29)
Our prior studies have shown an association between the deaths of children and consumption of Cassia occidentalis (CO) seeds. However, the chemicals responsible for the CO poisoning are not known. Therefore, the present study was designed to identify the key
Sing Teang Kong et al.
PloS one, 9(9), e108190-e108190 (2014-09-26)
To facilitate therapeutic monitoring of antiepileptic drugs (AEDs) by healthcare professionals for patients with epilepsy (PWE), we applied a GC-MS assay to measure three AEDs: carbamazepine (CBZ), phenytoin (PHT) and valproic acid (VPA) levels concurrently in one dried blood spot
Magda Caban et al.
Journal of chromatography. A, 1346, 107-116 (2014-05-13)
This paper discusses a new silylating reagent - dimethyl(3,3,3-trifluoropropyl)silyldiethylamine (DIMETRIS) - for the derivatisation of non-steroidal anti-inflammatory drugs (NSAIDs) prior to GC-MS analysis. DIMETRIS reacts with seven target compounds (diclofenac, ibuprofen, ketoprofen, naproxen, flurbiprofen and paracetamol, as well as salicylic
Toshiaki Yoshida
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 20(1), 71-76 (2015-01-15)
A fluorine-containing pyrethroid metofluthrin is widely used recently in mosquito repellents. The urinary excretion kinetics of its metabolites was evaluated in rats to establish an optimal biomarker for monitoring metofluthrin exposure of the general population. After metofluthrin had been administered
H Miao et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 27(11), 1497-1506 (2010-08-12)
A method was developed for the simultaneous determination of melamine, ammeline, ammelide, and cyanuric acid in egg using gas chromatography-tandem mass spectrometry (GC-MS/MS). The samples were first extracted by the solution of diethylamine-water-acetonitrile (10:40:50, v/v/v). Clean-up employed an 'On Guard
Caroline S Rempe et al.
PloS one, 10(5), e0123925-e0123925 (2015-05-09)
The aqueous extract of yerba mate, a South American tea beverage made from Ilex paraguariensis leaves, has demonstrated bactericidal and inhibitory activity against bacterial pathogens, including methicillin-resistant Staphylococcus aureus (MRSA). The gas chromatography-mass spectrometry (GC-MS) analysis of two unique fractions
Pavani P Nadiminti et al.
Protoplasma, 252(6), 1475-1486 (2015-02-26)
Electron microscopy techniques such as transmission electron microscopy (TEM) and scanning electron microscopy (SEM) have been invaluable tools for the study of the micromorphology of plant cuticles. However, for electron microscopy, the preparation techniques required may invariably introduce artefacts in
Thermal analysis of disulfonated poly (arylene ether sulfone) plasticized with poly (ethylene glycol) for membrane formation.
Oh HJ, et al.
Polymer, 55(1), 235-247 (2014)
Greg M Kowalski et al.
Biochemical and biophysical research communications, 463(4), 818-824 (2015-06-19)
Cardiac metabolism is thought to be altered in insulin resistance and type 2 diabetes (T2D). Our understanding of the regulation of cardiac substrate metabolism and insulin sensitivity has largely been derived from ex vivo preparations which are not subject to the
Yiwei Li et al.
Lab on a chip, 15(15), 3203-3210 (2015-07-02)
Active control over the cell gradient is essential for understanding biological systems and the reconstitution of the functionality of many types of tissues, particularly for organ-on-a-chip. Here, we propose a three-dimensional (3D) microfluidic strategy for generating controllable cell gradients. In
Andreas Üllen et al.
Biochemical pharmacology, 93(4), 470-481 (2015-01-13)
Hypochlorous acid added as reagent or generated by the myeloperoxidase (MPO)-H2O2-Cl(-) system oxidatively modifies brain ether-phospholipids (plasmalogens). This reaction generates a sn2-acyl-lysophospholipid and chlorinated fatty aldehydes. 2-Chlorohexadecanal (2-ClHDA), a prototypic member of chlorinated long-chain fatty aldehydes, has potent neurotoxic potential
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