ADC and bioconjugation

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Choosing the right crosslinker for your biochemical or bioconjugation research can be challenging. Our selection guide can help you find the perfect match for your applications.

Polybrene^® Technical Bulletin

Polybrene® neutralizes red blood cell charge, a vital anti-heparin agent in various laboratory applications.

Introduction to Click Chemistry

Click chemistry is an approach to the synthesis of drug-like molecules that can accelerate the drug discovery process by using a few practical and reliable reactions.

Staudinger Ligation

Azides react with triarylphosphines to form iminophophoranes, a chemoselective synthetic method known as Staudinger Ligation.

Copper-Free Click Chemistry

Copper-free click chemistry is an alternative approach to click chemistry that proceeds at a lower activation barrier and is free of cytotoxic transition metal catalysts.

Trifunctional Probe Building Blocks

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

Triazolylphenylglyoxal Reagents: Bioconjugation

Chemical ligation modifies biological macromolecules for biotech and medicine, expanding functional material development.

GlycoProfile™ Azido Sugars

GlycoProfile™ Azido Sugar portfolio offers peracetylated azido sugars for glycan structure modification via chemical or biosynthetic pathways.

Guanylation of Amines

Introduce guanidinyl group using guanylating reagents like bis(tert-butoxycarbonyl)thiopseudourea, polymer-bound, from substituted amines.

Click Chemistry in Drug Discovery

Explore the principles and applications of click chemistry in drug discovery, highlighting efficient reactions that streamline the synthesis of bioactive compounds.