The Caco-2 permeability assay provides a measure of the permeability of a test compound across the intestinal barrier and its potential for interactions with drug transporters. We provide permeability assays for small molecule formulations such as pharmaceuticals, industrial chemicals and
The mitochondrial toxicity assays provide a means to measure mitochondrial dysfunction due to the toxic effect of a test compound. We provide mitochondrial toxicity assays for all small molecule formulations such as pharmaceuticals, industrial chemicals and consumer products.
WST-1 assay protocol for measuring cell viability, proliferation, activation and cytotoxicity. Instructions for WST-1 reagent preparation and examples of applications. Frequently asked questions and troubleshooting guide for WST-1 assay.
The metabolic stability assays provide a means to measure the rate of disappearance of a test compound over time in either microsomal or hepatocyte incubations, and these data are used to calculate intrinsic clearance.
The kidney transporter assays provide a means to assess whether a test compound is a potential substrate or inhibitor of specific drug transporters within the kidney. We provide kidney transporter assays for small molecule formulations such as pharmaceuticals, industrial chemicals
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