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Lysophospholipid Receptors
Sigma-Aldrich offers many products related to lysophospholipid receptors for your research needs.
Calcium Channels
We offers many products related to calcium channels for your research needs.
PDGFR
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Vasoactive Intestinal Peptide Receptors
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JAKs
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Calcitonin Gene-Related Peptides
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Glutamate Receptors (Ion Channel Family)
We offers many products related to ion channel family glutamate receptors for your research needs.
Prostanoid Receptors
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Vasopressin and Oxytocin Receptors
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Dopamine, Norepinephrine and Ephinephrine Synthesis
Dopamine-β-hydroxylase is located inside amine storage vesicles of norepinephrine neurons. Dopamine is actively transported from the cytoplasm into the vesicles. As the enzyme is a copper containing protein, its activity can be inhibited by copper chelating agents, such as diethyldithiocarbamate
Leukotriene Receptors
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β-Adrenoceptors
β-Adrenoceptors are activated either by norepinephrine or epinephrine. Learn more about the role of β-adrenoceptors in protein expression, cell signaling, and metabolism research.
EGFR
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Excitatory Amino Acid Transporters
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Glutamate/GABA Synthesis and Metabolism
Glutamine is a common precursor for the biosynthesis of both glutamate and GABA. Glutamine can be transported in and out of neurons and astrocytes utilizing different glutamine carriers. The neurotransmitter glutamate can be synthesized from glutamine by the action of
PKA & PKG
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InsR
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Cholesterol Esterification
Cholesterol undergoes esterification to improve transport. Cholesterol esters are more easily packaged into the interior of lipoproteins - increasing the quantity that can be readily transported in the blood stream.
Mitochondrial Stress and ROS
Oxidative stress is mediated, in part, by reactive oxygen species produced by multiple cellular processes and controlled by cellular antioxidant mechanisms such as enzymatic scavengers or antioxidant modulators. Free radicals, such as reactive oxygen species, cause cellular damage via cellular.
Troponin
Troponin together with tropomyosin, regulate the binding of myosin to actin. Troponin is a trimeric protein composed of Troponin subunits I, C and T. Troponin C binds calcium ions, Troponin T binds to tropomyosin and troponin I binds
Adenylyl Cyclase
Adenylyl cyclases occur throughout the animal kingdom and play diverse roles in cell regulation. In bacteria, the enzyme may be regulated in response to nutrients or it may constitute a toxic factor in mammals, as with adenylyl cyclases of B.
Glycine Receptors
The amino acid glycine is a major inhibitory neurotransmitter in the vertebrate CNS. Glycinergic synapses are particularly abundant in spinal cord and brain stem, but are also found in higher brain regions including the hippocampus. The inhibitory actions of glycine
Cholesterol Biosynthesis Regulation
The amount of cholesterol that is synthesized in the liver is tightly regulated by dietary cholesterol levels. LDL receptors regulate the cellular transport of lipid rich low density lipoprotein (LDL) particles.
Growth Factors and Cytokines: Classification and Nomenclature
Growth factors and cytokines have historically been classified into ‘families’ based on their apparent activity and/or impact on a given cell type, system, or tissue.
Characteristic Metabolites for Inborn Errors of Amino Acid Metabolism
Inborn errors of metabolism are caused by changes in specific enzymatic reactions and hundreds of different such alterations, which affect about 1 of every 5000 newborns, have been characterized.
Sodium Channels
Voltage-gated sodium channels are present in most excitable cell membranes and play an important role in generating action potentials.
Myelin Associated Glycoprotein (MAG)
Myelin Associated Glycoprotein (MAG) is a type I transmembrane glycoprotein containing five Ig-like domains in its extracellular domain. It is an adhesion molecule belonging to the immunoglobin superfamily.
Glycogen Synthase Kinase 3 (GSK-3) Overview
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Cannabinoid Receptors
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Adenosine Receptors
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