Cell signaling

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Spectrin is the major component of the protein network, which covers the cytoplasmic surface of vertebrate, erythrocyte membranes. It is a high molecular weight heterodimer, composed of two subunits (molecular weights of approximately 230 kDa and 250 kDa)

Actinin

Introduction about α-Actinin protein present in both muscle and non-muscle cells.

Superoxide Dismutase

Enzyme Explorer Product Application Index for Superoxide Dismutase offered by us online. Superoxide Dismutase (SOD) catalyzes the reduction of superoxide anions to hydrogen peroxide.

Glycosylphosphatidylinisotol-anchored Glycoproteins Overview

GPI Anchored Glycoproteins

Glycogen Synthase Kinase 3 (GSK-3) Overview

Glycogen synthase kinase 3 (GSK-3) is a highly conserved family of serine/threonine kinases for over 100 proteins in many pathways. See a list of accepted GSK-3 modulators and related products.

P2 Receptors: P2Y G-Protein Family Overview

Surface receptors for extracellular nucleotides are called P2 receptors. Learn more about P2Y G protein-coupled receptors, GPCRs, and ionotropic P2 receptors (P2X ligand-gated ion channels, LGICs).

Lipopolysaccharides for Research – Structure, Function & Applications

Explore the structure, function, and diverse applications of Lipopolysaccharides. Discover their role in bacteria, serological specificity, and research potential.

PDGFR

We offers many products related to PDGFR for your research needs.

Prostanoid Receptors

We offer many products related to prostanoid receptors for your research needs.

Glutamate Receptors (Ion Channel Family)

We offers many products related to ion channel family glutamate receptors for your research needs.

Potassium Channels

We offer many products related to potassium channels for your research needs.

Sodium Channels

Voltage-gated sodium channels are present in most excitable cell membranes and play an important role in generating action potentials.

Cannabinoid Receptors

We offer many products related to cannabinoid receptors for your research needs.

Glutamate Receptors (G Protein Family)

Sigma-Aldrich offers many products related to G-protein family glutamate receptors for your research needs.

Discover Bioactive Small Molecules for Lipid Signaling Research

β-Adrenoceptors

β-Adrenoceptors are activated either by norepinephrine or epinephrine. Learn more about the role of β-adrenoceptors in protein expression, cell signaling, and metabolism research.

Leukotriene Receptors

We offer many products related to leukotriene receptors for your research needs.

Lysophospholipid Receptors

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P2 Receptors: P2X Ion Channel Family

We offer many products related to P2X ion channel family receptors for your research needs.

Vasopressin and Oxytocin Receptors

Sigma-Aldrich offers many products related to vasopressin and oxytocin receptors for your research needs.

Nuclear Receptors (Non-Steroids)

We offer many products related to non-steroid nuclear receptors for your research needs.

Serotonin Receptors

We offer many products related to serotonin receptors for your research needs.

FGFR

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EGFR

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Dopamine, Norepinephrine and Ephinephrine Synthesis

Dopamine-β-hydroxylase is located inside amine storage vesicles of norepinephrine neurons. Dopamine is actively transported from the cytoplasm into the vesicles. As the enzyme is a copper containing protein, its activity can be inhibited by copper chelating agents, such as diethyldithiocarbamate

Glycosphingolipids

Phosphoprotein Phosphatases (Tyrosine)

Protein tyrosine phosphatases' catalytic mechanism involves transient phosphorylation.

Troponin

Troponin together with tropomyosin, regulate the binding of myosin to actin. Troponin is a trimeric protein composed of Troponin subunits I, C and T. Troponin C binds calcium ions, Troponin T binds to tropomyosin and troponin I binds

Adenylyl Cyclase

Roles of adenylyl cyclases in cell regulation across different organisms.

Mitochondrial Stress and ROS

Cellular oxidative stress is countered by enzymatic scavengers and antioxidant modulators against reactive oxygen species damage.

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