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KitAlysis™ High-Throughput Screening Platform

KitAlysis High-Throughput Screening Kits provide solution to efficiently identify or optimize suitable catalytic reaction conditions. Chemist can rapidly run 24 unique micro scale reactions in parallel with tailored conditions.

Second-Generation, Designer-Surfactant Kits: Aqueous Reactions in a Box

Reactions once dependent on organic solvents are now being performed in water to eliminate the contributions of organic solvents to chemical waste – and the methodology just became easier with next-generation designer surfactant kits.

Asymmetric Hydrogenation

Asymmetric hydrogenation plays an important role in today’s synthesis world. Knowles and Noyori pioneered this field and were rewarded with the Nobel Prize in 2001 for their work.

Oxidizing and Reducing Agents

Oxidation and reduction reactions are some of the most common transformations encountered in organic synthesis

Azide Building Blocks for Chemical Ligation

Chemoselective ligation strategies are a key success factor for chemical biology research. Ligation techniques open pathways to fully synthetic large peptides and even proteins.

CBS Catalysts

we are pleased to offer both enatiomers of 2-methyl-CBS-oxazaborolidine as a dry reagent, in addition to our current offerings as a 1M solution in toluene.

CBILS©

The use of CBILS© – Carbonate Based Ionic Liquid Synthesis – developed by the Austrian company proionic, offers one of the simplest, yet most elegant synthetic methods for the production of ionic liquids

Organosilanes for Cross-coupling

Over the past several years, Pd-catalyzed cross-coupling of silicon compounds has rapidly gained acceptance as a suitable alternative to more commonly known methods such as: Stille (Sn), Kumada (Mg), Suzuki (B), and Negishi (Zn) cross-couplings.

Metal Scavengers

Metal compounds are widely used in organic and medicinal chemistry as either reactants or catalysts. Since most metal ions have physiological activities, reducing residual metal levels has become a key step in syntheses of bioactive compounds.

Leighton’s Chiral Allylation Reagents

An article regarding Leighton’s Chiral Allylation Reagents.

Chiral Amines in Asymmetric Synthesis

Chiral amines have found widespread application in asymmetric synthesis serving, for instance, as chiral bases in enantioselective deprotonation reactions or being valuable substances for resolving racemic mixtures of acids.

Lithium Aminoborohydride (LAB) Reagents

Lithium aminoborohydride (LAB) reagents are a new class of powerful and selective reagents developed in the laboratory of Professor Bakthan Singaram at the University of California, Santa Cruz.

Ynamides: Versatile and Enabling Building Blocks for Chemical Synthesis

The development of original and versatile reagents in modern organic synthesis is of crucial importance for the design of new chemical transformations that enable the fast and efficient assembly of a variety of complex molecules.

Asymmetric Reduction of Ketones

The enantioselective reduction of ketones to alcohols gives access to a pool of chiral building blocks that can be used for the synthesis of natural products. Adolfsson and co-workers reported a novel class of ligands, based on a pseudo-dipeptide, for

Mild Mg – Halogen Exchange

Substantial progress has been made in magnesium–halogen exchange reactions used for the preparation of functionalized Grignard reagents containing sensitive moieties such as ester or cyano groups.

Chiral Phosphoric Acids: Versatile Organocatalysts with Expanding Applications

TRIP and TiPSY Chiral Phosphoric Acid Catalysts

Selective Metalations

Selective Metalations using i-PrMgCl·LiCl and s-BuMgCl·LiCl

Greener Methods: Catalytic Amide Bond Formation

We are proud to offer a number of products used in catalytic amidation technology.

Drying Agents

Many products such as aluminas, silicas and molecular sieves can be employed as reasonably effective drying agents which can usually be conveniently regenerated. Current chemical literature reflects an active interest in the drying process, and even the method by which

Asymmetric Allylic Alkylation

Palladium-catalyzed asymmetric allylic alkylation (AAA) has proven to be an exceptionally powerful method for the efficient construction of stereogenic centers.

Super Silyl Protecting Groups

The super silyl group is a powerful tool for the synthetic chemist, showing great efficacy in various carbon–carbon bond forming reactions.

Ionic Liquids Properties & Applications

Facile and Rapid Chiral Resolution with ChiroSolv Kits

Our company is pleased to partner with ChiroSolve, Inc. to offer, through an exclusive distribution agreement, a series of ready-to-use kits for chiral resolution of racemates.

Dietary Terpenes

Terpenes comprise the largest and most diverse class of secondary metabolites; approximately 55,000 compounds have been identified to date.

Organic Azides and Azide Sources

Since the preparation of the first organic azide, phenyl azide, by Peter Griess in 1864 this energy-rich and versatile class of compounds has enjoyed considerable interest.

Benzotriazole Reagents

New Benzotriazole Reagents have commonly employed as a leaving group used extensively as a novel sythetic auxillary.

Functionalized Alkynes

Alkynes contain a highly versatile functional group that may be utilized for numerous reactions such as electrophilic additions of hydrogen, halogens, hydrogen halides, or water; metathesis; hydroboration; oxidative cleavage; C–C coupling; and cycloadditions

ChiPros Chiral Alcohols

Chiral alcohols form a versatile class of chiral synthons, since they can be incorporated into the API structures directly as esters or ethers.

Alkali Metal Silica Gels from SiGNa

SiGNa Chemistry has recently developed a technology for encapsulating alkali metals into nano-structured porous oxides to create stable, free flowing powders with varying reactivities (based on the intended application).

Functionalized Silica Gels for Organic Synthesis

Functionalized silica gel is used in size-exclusion chromatography of cationic polymers and in the separation of sugars, steroids, cholesterol, and triglycerides.

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