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CRISPR/Cas9 Products and Services
Synonym: CRISPR, CRISPRs, Cas9, Crispr RNA, Crispr/Cas System, Synthetic CRISPR, crRNA, tracrRNA
SMCxPRO™ Immunoassay Instrument and SMC™ Kits
High Sensitivity Protein Measurement at the fg/mL level Synonym: SMC, Singulex, single molecule counting, xPRO
Device Validation
Device Validation
Calculators & Apps
Calculators & Apps
Pharma Microbiology Method Validation
Our pharma microbiology testing device validation protocols provide correct documentation for audits and with regulatory authorities. When we are on-site, our validation engineers ask the right questions, understand your application, and the validation requirements of your equipment.
Asia Pacific
Asia Pacific Region
Pharma Microbiology Testing Device Validation
Our pharma microbiology testing device validation protocols provide correct documentation for audits and with regulatory authorities. When we are on-site, our validation engineers ask the right questions, understand your application, and the validation requirements of your equipment.
Americas
Americas region
Suzuki–Miyaura Coupling Reagents
This brochure contains a comprehensive selection of boronic acids, boronic acid esters, diboron esters, and transition-metal catalysts useful for the Suzuki–Miyaura coupling reaction
Carbohydrate-Catalyzed Enantioselective Alkene Diboration
Enantioselective alkene diboration is a valuable strategy for transforming unsaturated hydrocarbons into useful chiral building blocks.
Reducing Organic Photoredox Catalysts for Visible Light-Driven Polymer and Small Molecule Synthesis
Photoredox catalysis is a powerful synthetic methodology to form challenging covalent bonds using light irradiation. It is effective for light-driven polymer and small molecule synthesis.
Ellman's Sulfinamides
Ellman's sulfinamide is available in both enantiomeric and racemic forms for your research. This versatile and useful auxiliary has found extensive use both in academics and industry.
Polybrene® Technical Bulletin
Polybrene® is a well-known anti-heparin agent. Also known as 1,5-dimethyl-1,5-diazaundecamethylene polymethobromide and hexadimethrine bromide, this positively charged polymer produces non-specific red blood cell agglutination by neutralizing the red blood cell net negative charge.
Greener Chemistry: Methods and Products for Amide Bond Formation
Amide bonds are ubiquitous in both nature and industrial applications. They are vital to the structure and function of biological macromolecules and polymers. The importance of this functionality has resulted in numerous approaches to its formation, ranging from stoichiometric activation
Resins for the Fmoc-/tBu-Synthesis of Peptide Acids
The TFA-labile Wang resin is a standard support for batch synthesis of peptide acids following the Fmoc-/tBu-protection scheme.
Methyl Isotope-Labeling of Proteins from NMR-Bio
Methyl groups are ideal probes for studying protein structure and function by NMR. Choose among user-friendly kits for isotope labeling of a single type or multiple types of methyl groups.
Coupling Reagents
In principle, the seemingly simple formation of a peptide bond can be accomplished using all the procedures available in organic chemistry for the synthesis of carboxylic acid amides. However, due to the presence of various functional groups in natural and
Staudinger Ligation
Originally reported by Staudinger and Meyer, azides react readily with triarylphosphines to form the corresponding iminophophoranes. The Staudinger Ligation: A High-Yield, Chemoselective, and Mild Synthetic Method.
Resins for the Synthesis of C-Terminal Modified Peptides
Hydroxymethylbenzoic acid (HMBA) is a useful and versatile benzyl ester derived linker, completely resistant to acids (even to liquid HF) but easily cleavable by a variety of nucleophilic reagents to give access to peptides with diverse C-terminal functionalities.
Baran Diversinates™
The synthesis of heteroaromatic and aromatic compounds is at the heart of the chemical industry. The ever-growing demand for new chemical entities, coupled with dwindling resources and time constraints allotted to any given research project, a rapid way to diversify
C–H Amination
The Du Bois group at Stanford University has made substantial progress within the field of Rh-catalyzed C–H amination via oxidative cyclization of carbamate, sulfamate, sulfamide, urea, and guanidine substrates to give 1,2- and 1,3-heteroatom motifs masked in the form of
Fmoc Resin Cleavage and Deprotection
Fmoc resin cleavage and deprotection follows the difficult task of detaching the peptide from the resin support and removing all the side-chain protecting groups of the amino acid residues to yield the desired peptide.
Chemoselective Purification Tags
Our long peptide purification utilizes a combination of chemoselective purification tags and standard RP-HPLC. The method is especially effective at removing impurities that are closely eluting or hidden under the isolated product peak
Counting of Cells
Trypan blue method of cell counting is inexpensive and readily available method. The method is based on principle that living cells exclude trypan blue dye and appear bright, while dead cells take up dye and appear blue. Watch video to
Glucose in Cell Culture
Importance and uses of glucose in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures
Glutathione in Cell Culture
This page providesinsights on how tripeptide, glutathione, and other important cell culture components affect the performance of serum-free, protein-free and animal protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies.
Knoevenagel Condensation Reaction
Knoevenagel Condensation is an organic reaction named after Emil Knoevenagel. It is a classic C-C bond formation reaction and a modification of the Aldol Condensation.
Fluorescent Labeling of Peptides
Fluorescent Labeling of Peptides
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