Merck

Conversion of indanone oximes into isocarbostyrils.

Bioorganic & medicinal chemistry letters (2006-10-27)
Yasuhiro Torisawa, Shinji Aki, Jun-ichi Minamikawa
ABSTRACT

New and effective method for the Beckmann rearrangement of indanone oxime mesylate is described, in which a selective and controlled production of the isomeric isocarbostyrils is achieved.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Isocarbostyril, 98%
Sigma-Aldrich
Methanesulfonyl chloride, purum, ≥98.0% (AT)
Sigma-Aldrich
Methanesulfonyl chloride, ≥99.7%