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Merck

ABCD4

ATP-binding cassette, sub-family D (ALD), member 4

Sinónimos:
ABC41, EST352188, MAHCJ, P70R, P79R, PMP69, PXMP1L
Especie:
ID UniProtKB:
ID del gen:
  • Human(5826) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding. [provided by RefSeq, Jul 2008]
  • Mouse(19300) ATP-binding cassette, sub-family D (ALD), member 4
  • Rat(299196) ATP-binding cassette, subfamily D (ALD), member 4
  • domestic guinea pig(100722270) ATP-binding cassette, sub-family D (ALD), member 4
  • naked mole-rat(101701894) ATP-binding cassette, sub-family D (ALD), member 4
  • Zebrafish(767748) ATP-binding cassette, sub-family D (ALD), member 4
  • Horse(100056775) ATP-binding cassette, sub-family D (ALD), member 4
  • chicken(423349) ATP-binding cassette, sub-family D (ALD), member 4
  • cow(528646) ATP-binding cassette, sub-family D (ALD), member 4
  • sheep(101106333) ATP-binding cassette, sub-family D (ALD), member 4
  • domestic cat(101091287) ATP-binding cassette, sub-family D (ALD), member 4
  • dog(490781) ATP-binding cassette, sub-family D (ALD), member 4

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-ABCD4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-ABCD4 antibody produced in rabbit, IgG fraction of antiserum,
Reactividad de especies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
western blot

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Abcd4,
Especie
mouse
MISSION® esiRNA, targeting human ABCD4,
Especie
human