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Merck

CACNB1

calcium channel, voltage-dependent, beta 1 subunit

Sinónimos:
CAB1, CACNLB1, CCHLB1
Especie:
ID UniProtKB:
ID del gen:
  • Human(782) Summary: The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(12295) calcium channel, voltage-dependent, beta 1 subunit
  • Rat(50688) calcium channel, voltage-dependent, beta 1 subunit
  • Zebrafish(436925) calcium channel, voltage-dependent, beta 1 subunit
  • cow(327703) calcium channel, voltage-dependent, beta 1 subunit
  • sheep(101122960) calcium channel, voltage-dependent, beta 1 subunit
  • domestic cat(101089057) calcium channel, voltage-dependent, beta 1 subunit
  • domestic guinea pig(100721141) calcium channel, voltage-dependent, beta 1 subunit
  • naked mole-rat(101714578) calcium channel, voltage-dependent, beta 1 subunit
  • dog(491030) calcium channel, voltage-dependent, beta 1 subunit

Custom & Knockdown Gene Products

Small Molecule - Allosteric Modulator

Número de producto
Descripción
Especie
Gabapentin, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Gabapentin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human
Pregabalin, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Gabapentin solution, 10 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-CACNB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-Calcium Channel (β1 subunit) antibody produced in rabbit, ~1 mg/mL, fractionated antiserum, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
western blot

Small Molecule - Blocker

Número de producto
Descripción
Especie
Bepridil hydrochloride, powder,
Especie
human
Terodiline hydrochloride, ≥98% (HPLC), solid,
Especie
human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human CACNB1,
Especie
human
MISSION® esiRNA, targeting mouse Cacnb1,
Especie
mouse