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Merck

DAND5

DAN domain family member 5, BMP antagonist

Sinónimos:
CER2, CERL2, CKTSF1B3, COCO, CRL2, DANTE, GREM3, SP1
Especie:
ID UniProtKB:
ID del gen:
  • Human(199699) Summary: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry. [provided by RefSeq, Jul 2008]
  • Mouse(23863) DAN domain family, member 5
  • Rat(685719) DAN domain family, member 5
  • domestic guinea pig(100727384) DAN domain family member 5, BMP antagonist
  • Zebrafish(791454) DAN domain family, member 5
  • dog(484921) DAN domain family, member 5
  • naked mole-rat(101721262) DAN domain family member 5, BMP antagonist

Custom & Knockdown Gene Products

ELISA

Número de producto
Descripción
Especie
Human DAND5 / DAN Domain Family Member 5 ELISA Kit, ,
Especie
human

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-DAND5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-DAND5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Dand5,
Especie
mouse