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Merck

ESPL1

extra spindle pole bodies homolog 1 (S. cerevisiae)

Sinónimos:
ESP1, SEPA
Especie:
ID UniProtKB:
ID del gen:
  • Human(9700) Summary: Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids (Sun et al., 2009 [PubMed 19345191]
  • Mouse(105988) extra spindle poles-like 1 (S. cerevisiae)
  • Rat(315330) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • chicken(425536) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • Zebrafish(797406) extra spindle poles like 1
  • domestic guinea pig(100733255) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • naked mole-rat(101723260) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • Domestic Rabbit(100356105) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • domestic cat(101084118) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • Horse(100063779) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • cow(506740) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • sheep(101105898) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • dog(607879) extra spindle pole bodies homolog 1 (S. cerevisiae)

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-ESPL1 antibody produced in mouse, clone 6H6, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunohistochemistry

western blot
Anti-SEPARASE antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse
Aplicación
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-ESPL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human ESPL1,
Especie
human
MISSION® esiRNA, targeting mouse Espl1,
Especie
mouse