LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
Sinónimos:
DFNB63, LRRC51
Especie:
ID UniProtKB:
ID del gen:
- Human(220074) Summary: This gene includes two transcript forms. The short form has one open reading frame (ORF), which encodes the leucine-rich repeats (LRR)-containing protein of unknown function. This protein is called LRTOMT1 or LRRC51. The long form has two alternative ORFs; the upstream ORF has the same translation start codon as used in the short form and the resulting transcript is a candidate for nonsense-mediated decay, and the downstream ORF encodes a different protein, which is a transmembrane catechol-O-methyltransferase and is called LRTOMT2, TOMT or COMT2. The COMT2 is essential for auditory and vestibular function. Defects in the COMT2 can cause nonsyndromic deafness. Alternatively spliced transcript variants from each transcript form have been found for this gene. [provided by RefSeq, Sep 2012]
- dog(485212) leucine rich transmembrane and O-methyltransferase domain containing
- chicken(100857436) transmembrane O-methyltransferase
- Zebrafish(767801) leucine rich transmembrane and O-methyltransferase domain containing
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-LRTOMT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot