MBD5
methyl-CpG binding domain protein 5
Sinónimos:
MRD1
Especie:
Human MBD5 (55777), Mouse Mbd5 (109241), Rat Mbd5 (311026), Domestic Rabbit MBD5 (100358608), sheep MBD5 (101121829), naked mole-rat Mbd5 (101708541), domestic guinea pig Mbd5 (100731243), cow MBD5 (541084), Thale Cress MBD5 (823811), chicken MBD5 (424308) ...Más
ID UniProtKB:
ID del gen:
- Human(55777) Summary: This gene encodes a member of the methyl-CpG-binding domain (MBD) family. The MBD consists of about 70 residues and is the minimal region required for a methyl-CpG-binding protein binding specifically to methylated DNA. In addition to the MBD domain, this protein contains a PWWP domain (Pro-Trp-Trp-Pro motif), which consists of 100-150 amino acids and is found in numerous proteins that are involved in cell division, growth and differentiation. Mutations in this gene cause mental retardation autosomal dominant type 1. Haploinsufficiency of this gene is associated with a syndrome involving microcephaly, intellectual disabilities, severe speech impairment, and seizures. Alternatively spliced transcript variants have been found, but their full-length nature is not determined. [provided by RefSeq, Mar 2010]
- Mouse(109241) methyl-CpG binding domain protein 5
- Rat(311026) methyl-CpG binding domain protein 5
- Domestic Rabbit(100358608) methyl-CpG binding domain protein 5
- sheep(101121829) methyl-CpG binding domain protein 5
- naked mole-rat(101708541) methyl-CpG binding domain protein 5
- domestic guinea pig(100731243) methyl-CpG binding domain protein 5
- cow(541084) methyl-CpG binding domain protein 5
- Thale Cress(823811) methyl-CPG-binding domain protein 5
- chicken(424308) methyl-CpG binding domain protein 5
- Horse(100049894) methyl-CpG binding domain protein 5
- domestic cat(101098244) methyl-CpG binding domain protein 5
- dog(483910) methyl-CpG binding domain protein 5
- Zebrafish(100009623) methyl-CpG binding domain protein 5
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-MBD5, from rabbit, purified by affinity chromatography,
Reactividad de especies
human, mouse, rat
Aplicación
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-MBD5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Monoclonal Anti-MBD5 antibody produced in mouse, clone 4A12-1B6, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
esiRNA
Número de producto
Descripción
Especie