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Merck

NEFL

neurofilament, light polypeptide

Sinónimos:
CMT1F, CMT2E, NF-L, NF68, NFL
Especie:
ID UniProtKB:
ID del gen:
  • Human(4747) Summary: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
  • Mouse(18039) neurofilament, light polypeptide
  • Rat(83613) neurofilament, light polypeptide
  • chicken(419528) neurofilament, light polypeptide
  • sheep(101119539) neurofilament, light polypeptide
  • cow(281348) neurofilament, light polypeptide
  • dog(477378) neurofilament, light polypeptide
  • naked mole-rat(101704332) neurofilament, light polypeptide
  • domestic cat(101081039) neurofilament, light polypeptide
  • domestic guinea pig(100731797) neurofilament, light polypeptide

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anticuerpo anti-neurofilamento L, serum, Chemicon®,
Reactividad de especies
bovine, canine, feline, human, mouse, pig, rat
Aplicación
immunocytochemistry
immunohistochemistry

western blot
Monoclonal Anti-Neurofilament 68 antibody produced in mouse, clone NR4, ascites fluid,
Reactividad de especies
chicken, human, pig, rat
Aplicación
immunohistochemistry
microarray

western blot
Neurofilament (2F11) Mouse Monoclonal Antibody, ,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-Neurofilament 70 kDa Antibody, clone DA2, culture supernatant, clone DA2, Chemicon®,
Reactividad de especies
bovine, human, mouse, pig, rat
Aplicación
immunocytochemistry
immunohistochemistry

western blot
Anti-phospho-NFL (Ser473) Antibody, clone 4F8, clone 4F8, from mouse,
Reactividad de especies
bovine, human, mouse, porcine, rat, rhesus macaque
Aplicación
immunohistochemistry
western blot

Proteins

Número de producto
Descripción
Especie
Neurofilament 70 kDa, porcine, ,
Especie

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human NEFL,
Especie
human