NELFA
negative elongation factor complex member A
Sinónimos:
NELF-A, WHSC2
Especie:
Human NELFA (7469), Mouse Nelfa (24116), Rat Nelfa (305455), domestic guinea pig Nelfa (100733233), naked mole-rat Nelfa (101708884), Zebrafish nelfa (559677)
ID UniProtKB:
ID del gen:
- Human(7469) Summary: This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. [provided by RefSeq, Jul 2008]
- Mouse(24116) negative elongation factor complex member A, Whsc2
- Rat(305455) negative elongation factor complex member A
- domestic guinea pig(100733233) negative elongation factor complex member A
- naked mole-rat(101708884) negative elongation factor complex member A
- Zebrafish(559677) negative elongation factor complex member A
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-NELFA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-NELFA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
ChIP
immunofluorescence
immunofluorescence
esiRNA
Número de producto
Descripción
Especie