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Merck

PRMT6

protein arginine methyltransferase 6

Sinónimos:
HRMT1L6
Especie:
ID UniProtKB:
ID del gen:
  • Human(55170) Summary: The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011]
  • Mouse(99890) protein arginine N-methyltransferase 6
  • Rat(295384) protein arginine methyltransferase 6
  • domestic cat(101093626) protein arginine methyltransferase 6
  • domestic guinea pig(100725259) protein arginine methyltransferase 6
  • cow(540228) protein arginine methyltransferase 6
  • Thale Cress(821541) protein arginine N-methyltransferase 6
  • naked mole-rat(101715374) protein arginine methyltransferase 6
  • sheep(101119859) protein arginine methyltransferase 6
  • Zebrafish(448867) protein arginine methyltransferase 6
  • dog(490133) protein arginine methyltransferase 6

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-PRMT6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
Anti-PRMT6 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, rat
Aplicación
ChIP
western blot
Anti- PRMT6 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-PRMT6 Antibody, clone 1Z10L6, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
western blot
Anti-PRMT6 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse, pig, rat
Aplicación
ELISA
western blot

Proteins

Número de producto
Descripción
Especie
PRMT6 active human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Especie
human
PRMT6 human, recombinant, expressed in FreeStyle 293-F cells, ≥70% (SDS-PAGE),
Especie
human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Prmt6,
Especie
mouse
MISSION® esiRNA, targeting human PRMT6,
Especie
human