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Merck

RIN2

Ras and Rab interactor 2

Sinónimos:
MACS, RASSF4
Especie:
ID UniProtKB:
ID del gen:
  • Human(54453) Summary: The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
  • Mouse(74030) Ras and Rab interactor 2
  • Rat(311494) Ras and Rab interactor 2
  • domestic guinea pig(100725411) Ras and Rab interactor 2
  • naked mole-rat(101723666) Ras and Rab interactor 2
  • Thale Cress(828626) E3 ubiquitin protein ligase RIN2
  • sheep(101123061) Ras and Rab interactor 2
  • cow(537459) Ras and Rab interactor 2
  • dog(477139) Ras and Rab interactor 2
  • domestic cat(101080627) Ras and Rab interactor 2
  • chicken(421246) Ras and Rab interactor 2

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-RIN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Rin2,
Especie
mouse