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Merck

SETMAR

SET domain and mariner transposase fusion gene

Sinónimos:
HsMar1, METNASE, Mar1
Especie:
ID UniProtKB:
ID del gen:
  • Human(6419) Summary: This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
  • Mouse(74729) SET domain without mariner transposase fusion
  • Rat(500281) SET domain without mariner transposase fusion
  • naked mole-rat(101704237) SET domain and mariner transposase fusion gene
  • domestic cat(101088560) SET domain without mariner transposase fusion
  • cow(511299) SET domain without mariner transposase fusion
  • Zebrafish(564575) SET domain without mariner transposase fusion
  • dog(476549) SET domain without mariner transposase fusion
  • sheep(101110273) SET domain gene

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-SETMAR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot

Proteins

Número de producto
Descripción
Especie
SETMAR, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human
Metnase (SETMAR) human, recombinant, expressed in FreeStyle 293-F cells, ≥30% (SDS-PAGE),
Especie
human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Setmar,
Especie
mouse
MISSION® esiRNA, targeting human SETMAR,
Especie
human