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Merck

SPACA1

sperm acrosome associated 1

Sinónimos:
SAMP32
Especie:
ID UniProtKB:
ID del gen:
  • Human(81833) Summary: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively. [provided by RefSeq, Jul 2008]
  • Mouse(67652) sperm acrosome associated 1
  • Rat(500432) sperm acrosome associated 1
  • domestic cat(101091941) sperm acrosome associated 1
  • chicken(421820) sperm acrosome associated 1
  • sheep(101112231) sperm acrosome associated 1
  • naked mole-rat(101703197) sperm acrosome associated 1
  • dog(611635) sperm acrosome associated 1
  • domestic guinea pig(100728130) sperm acrosome associated 1
  • cow(614884) sperm acrosome associated 1

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-SPACA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-SPACA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human SPACA1,
Especie
human
MISSION® esiRNA, targeting mouse Spaca1,
Especie
mouse