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Merck

SPPL2B

signal peptide peptidase like 2B

Sinónimos:
IMP-4, IMP4, PSH4, PSL1
Especie:
ID UniProtKB:
ID del gen:
  • Human(56928) Summary: This gene encodes a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(73218) signal peptide peptidase like 2B
  • Rat(362828) signal peptide peptidase-like 2B
  • sheep(101120828) signal peptide peptidase like 2B
  • domestic guinea pig(100719910) signal peptide peptidase like 2B
  • naked mole-rat(101708060) signal peptide peptidase like 2B
  • chicken(420056) signal peptide peptidase like 2B
  • dog(485071) signal peptide peptidase like 2B
  • domestic cat(101081277) signal peptide peptidase like 2B
  • cow(504285) signal peptide peptidase-like 2B

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-SPPL2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot