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Merck

TRIM21

tripartite motif containing 21

Sinónimos:
RNF81, RO52, SSA, SSA1
Especie:
ID UniProtKB:
ID del gen:
  • Human(6737) Summary: This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]
  • Mouse(20821) tripartite motif-containing 21
  • Rat(308901) tripartite motif-containing 21
  • Horse(100066782) tripartite motif containing 21
  • dog(485226) tripartite motif containing 21
  • cow(359715) tripartite motif containing 21
  • domestic cat(101098574) tripartite motif containing 21
  • domestic guinea pig(100729320) tripartite motif containing 21
  • sheep(101114640) tripartite motif containing 21
  • naked mole-rat(101709110) tripartite motif containing 21

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-TRIM21 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot
Anti-TRIM21 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-TRIM21 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
Reactividad de especies
human
Aplicación
western blot

Proteins

Número de producto
Descripción
Especie
RO-52 (SSA) human, recombinant, expressed in E. coli, liquid,
Especie
human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human TRIM21,
Especie
human
MISSION® esiRNA, targeting mouse Trim21,
Especie
mouse