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Merck

USP5

ubiquitin specific peptidase 5 (isopeptidase T)

Sinónimos:
ISOT
Especie:
ID UniProtKB:
ID del gen:
  • Human(8078) Summary: Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]
  • Mouse(22225) ubiquitin specific peptidase 5 (isopeptidase T)
  • Rat(297593) ubiquitin specific peptidase 5 (isopeptidase T)
  • chicken(418290) ubiquitin specific peptidase 5 (isopeptidase T)
  • domestic cat(101085296) ubiquitin specific peptidase 5 (isopeptidase T)
  • cow(505280) ubiquitin specific peptidase 5 (isopeptidase T)
  • naked mole-rat(101720419) ubiquitin specific peptidase 5 (isopeptidase T)
  • dog(486718) ubiquitin specific peptidase 5 (isopeptidase T)
  • sheep(101109954) ubiquitin specific peptidase 5 (isopeptidase T)
  • Zebrafish(406618) ubiquitin specific protease 5
  • Horse(100060068) ubiquitin specific peptidase 5 (isopeptidase T)
  • domestic guinea pig(100724997) ubiquitin specific peptidase 5 (isopeptidase T)

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-USP5 antibody produced in mouse, clone 4G4, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot
Anti-USP5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry

western blot
KD-Validated Anti Ubiquitin Specific Peptidase 5 Antibody, clone 24GB2480, Rabbit Monoclonal, clone 24GB2480, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human, rat
Aplicación
flow cytometry
immunofluorescence

western blot

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human USP5,
Especie
human
MISSION® esiRNA, targeting mouse Usp5,
Especie
mouse