Characterization and quality control of monoclonal antibodies (mAbs) is critical throughout the mAb workflow. It involves a series of quality control tests and assays to evaluate the physical and chemical properties of the mAb. These parameters are strictly monitored with mass spectrometry-based methods for quantitative and qualitative antibody characterization to determine the primary sequence, post-translational modifications (PTMs), charge variants, and other properties that can potentially impact the efficacy, stability, half-life, and safety of therapeutic mAbs.
Characterization and Quality Control
Characterization and Quality Control of Monoclonal Antibodies
Our comprehensive portfolio of high-quality products for peptide mapping, post-translational modification, intact mass analysis, titer determination analysis, and aggregate analysis provides everything you need for the characterization and analysis of monoclonal antibodies (mAbs) to reliably evaluate critical quality attributes (CQAs) and ensure mAb quality and efficacy.
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