39391

Sigma-Aldrich

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide

≥97.0% (T)

Sinónimos:
EDC, WSC, N-Ethyl-N′-(3-dimethylaminopropyl)carbodiimide
Empirical Formula (Hill Notation):
C8H17N3
Número de CAS:
Peso molecular:
155.24
Beilstein/REAXYS Number:
507429
Número de EC:
Número MDL:
ID de la sustancia en PubChem:

Nivel de calidad

100

ensayo

≥97.0% (T)

reaction suitability

reaction type: Coupling Reactions

aplicaciones

peptide synthesis: suitable

índice de refracción

n20/D 1.461

densidad

0.877 g/mL at 20 °C (lit.)

temp. de almacenamiento

−20°C

SMILES string

CCN=C=NCCCN(C)C

InChI

1S/C8H17N3/c1-4-9-8-10-6-5-7-11(2)3/h4-7H2,1-3H3

InChI key

LMDZBCPBFSXMTL-UHFFFAOYSA-N

Descripción general

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide is commonly used in combination with N-hydroxysuccinimide (NHS) in carbodiimide coupling reaction to activate carboxyl group for coupling with amines to form amides.

Aplicación

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide has been used for the surface functionalization of graphene quantum dots (GQDs) employed as sensing probes in Janus micromotors to detect enterobacterial contamination. It has also been used for the activation of folic acid, prior to its conjugation on silica nanoparticles.

Envase

50 mL in Sure/Seal™
10 mL in glass bottle

Otras notas

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 39391.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Palabra de señalización

Danger

hazcat

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Oral

storage_class_code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK Alemania

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Equipo de protección personal

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Certificado de Análisis

Certificado de origen

SENSITIVE MONITORING OF ENTEROBACTERIAL CONTAMINATION OF FOOD USING SELF-PROPELLED JANUS MICROSENSORS
Pacheco M
Analytical Chemistry, 90(4), 2912-2917 (2018)
Anthony C Y Yau et al.
Scientific reports, 7(1), 14998-14998 (2017-11-10)
Mineral oils are extensively used in our daily life, in food, cosmetics, biomedicine, vaccines and in different industrial applications. However, exposure to these mineral oils has been associated with immune adjuvant effects and the development of autoimmune diseases. Here we...
Michael J Taylor et al.
Journal of biomedical materials research. Part A, 107(10), 2195-2204 (2019-05-23)
Scaffolds composed of synthetic polymers such as poly(caprolactone) (PCL) are widely used for the support and repair of tissues in biomedicine. Pores are common features in scaffolds as they facilitate cell penetration. Various surface modifications can be performed to promote...
Immobilization of laccase on polymer grafted polytetrafluoroethylene membranes for biosensor construction.
Tastan E
Talanta, 84(2), 524-530 (2011)
Ruogu Qi et al.
Nature communications, 8(1), 2166-2166 (2017-12-20)
Advanced-stage epithelial ovarian cancers are amongst the most difficult to treat tumors and have proven to be refractory to most cytotoxic, molecularly targeted, or immunotherapeutic approaches. Here, we report that nanoparticle-drug conjugates (NDCs) of monomethyl auristatin E (MMAE) significantly increase...
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