11-Mercaptoundecanoic acid (MUA) is used as a self-assembled monolayer (SAM) which has a long alkane chain and carboxyl containing thiols. MUA is highly packed and has self-organized surface monolayers. It is a pH responsive ligand which facilitates the dispersion of nanoparticles into water and solvent based media.
MUA as a self-assembled monolayer (SAM) is used as a microfluidic integrated surface plasmon resonance (SPR) for detection and quantification of bacteria in medical diagnostics. It is also used to bio-functionalize the screen printed gold electrodes (SPGEs) that are used for the detection and quantification of dengue. It also forms monolayers on gold nanoparticles (AuNPs) attached via thiol groups. MUA incorporated AuNPs exhibit excellent fluorescence properties which may be used for metal ion detection in serum samples.