695211

Sigma-Aldrich

tBuMePhos

Sinónimos:
t-Butyl MePhos, 2-Di-tert-butylphosphino-2′-methylbiphenyl
Empirical Formula (Hill Notation):
C21H29P
Número de CAS:
Peso molecular:
312.43
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.22

reaction suitability

reagent type: ligand
reaction type: Arylations

reagent type: ligand
reaction type: Buchwald-Hartwig Cross Coupling Reaction

reagent type: ligand
reaction type: Heck Reaction

reagent type: ligand
reaction type: Reductions

Nivel de calidad

100

mp

90-95 °C

grupo funcional

phosphine

SMILES string

Cc1ccccc1-c2ccccc2P(C(C)(C)C)C(C)(C)C

InChI

1S/C21H29P/c1-16-12-8-9-13-17(16)18-14-10-11-15-19(18)22(20(2,3)4)21(5,6)7/h8-15H,1-7H3

InChI key

UJONYAVMBYXBJQ-UHFFFAOYSA-N

Envase

1 g in glass bottle
500 mg in glass bottle

Aplicación

A ligand for the palladium-catalyzed monoarylation of malonate esters, 1,3-diketones and isolated nitroalkanes.

Información legal

Usage subject to US Patents 6307087 and 6395916.

storage_class_code

13 - Non Combustible Solids

WGK Alemania

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificado de Análisis

Certificado de origen

David S Surry et al.
Chemical science, 2(1), 27-50 (2011-01-01)
Dialkylbiaryl phosphines are a valuable class of ligand for Pd-catalyzed amination reactions and have been applied in a range of contexts. This review attempts to aid the reader in the selection of the best choice of reaction conditions and ligand...
Ruben Martin et al.
Accounts of chemical research, 41(11), 1461-1473 (2008-07-16)
The cores of many types of polymers, ligands, natural products, and pharmaceuticals contain biaryl or substituted aromatic structures, and efficient methods of synthesizing these structures are crucial to the work of a broad spectrum of organic chemists. Recently, Pd-catalyzed carbon-carbon...
David S Surry et al.
Angewandte Chemie (International ed. in English), 47(34), 6338-6361 (2008-07-30)
Palladium-catalyzed amination reactions of aryl halides have undergone rapid development in the last 12 years, largely driven by the implementation of new classes of ligands. Biaryl phosphanes have proven to provide especially active catalysts in this context. This Review discusses...
Artículos
Buchwald phosphine ligands for C-C, C-N, and C-O bond formation.
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