810180P

Avanti

TopFluor® TMR PC

1-oleoyl-2-(6-((4,4-difluoro-1,3-dimethyl-5-(4-methoxyphenyl)-4-bora-3α,4α-diaza-s-indacene-2-propionyl)amino)hexanoyl)-sn-glycero-3-phosphocholine, powder

Empirical Formula (Hill Notation):
C53H82 BF2N4 O10P
Peso molecular:
1015.02
NACRES:
NA.25

ensayo

>99% (TLC)

formulario

powder

envase

pkg of 1 × 1 mg (810180P-1mg)

manufacturer/tradename

Avanti Polar Lipids 810180P

enviado en

dry ice

temp. de almacenamiento

−20°C

Descripción general

Tetramethylrhodamine (TMR) phosphatidylcholine (PC) is a fatty acid labeled fluorescent phospholipid. Phosphatidylcholine (PC) is the most abundant phospholipid in eukaryotes. It is the prime metabolite of glycerolipid metabolism.

Aplicación

TopFluor® TMR PC or 1-oleoyl-2-(6-((4,4-difluoro-1,3-dimethyl-5-(4-methoxyphenyl)-4-bora-3α,4α-diaza-s-indacene-2-propionyl)amino)hexanoyl)-sn-glycero-3-phosphocholine may be used for the formation of lipid membranes in microarrays.

Acciones bioquímicas o fisiológicas

TopFluor®-labeled lipids have spectral properties similar to tetramethylrhodamine (TMR).

Envase

5 mL Amber Glass Screw Cap Vial (810180P-1mg)

Información legal

TopFluor is a registered trademark of Avanti Polar Lipids, Inc.

RIDADR

NONH for all modes of transport

Certificado de Análisis
Rikiya Watanabe
Biochimica et biophysica acta. General subjects, 1864(2), 129330-129330 (2019-03-31)
Micro-chamber arrays enable highly sensitive and quantitative bioassays at the single-molecule level. Accordingly, they are widely used for ultra-sensitive biomedical applications, e.g., digital PCR and digital ELISA. However, the versatility of micro-chambers is generally limited to reactions in aqueous solutions...
Single-molecule analysis of phospholipid scrambling by TMEM16F
Rikiya W, et al.
Proceedings of the National Academy of Sciences of the USA, 115(12), 3066-3071 (2018)
Rikiya Watanabe et al.
Proceedings of the National Academy of Sciences of the United States of America, 115(12), 3066-3071 (2018-03-07)
Transmembrane protein 16F (TMEM16F) is a Ca2+-dependent phospholipid scramblase that translocates phospholipids bidirectionally between the leaflets of the plasma membrane. Phospholipid scrambling of TMEM16F causes exposure of phosphatidylserine in activated platelets to induce blood clotting and in differentiated osteoblasts to...
Microsystem for the single molecule analysis of membrane transport proteins
Rikiya W.
Biochimica et biophysica acta. General subjects, 1864(2), 129330-129330 (2020)
A phosphatidylinositol 4, 5-bisphosphate redistribution-based sensing mechanism initiates a phagocytosis programing.
Mu L, et al.
Nature Communications, 9(1), 4259-4259 (2018)

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