840044C

Avanti

Soy PI

L-α-phosphatidylinositol (Soy) (sodium salt), chloroform

Número de CAS:
NACRES:
NA.25

ensayo

>99% (TLC)

envase

pkg of 1 × 1 mL (840044C-10mg)
pkg of 1 × 2 mL (840044C-50mg)
pkg of 1 × 2.5 mL (840044C-25mg)

manufacturer/tradename

Avanti Polar Lipids 840044C

concentración

10 mg/mL (840044C-10mg)
10 mg/mL (840044C-25mg)
25 mg/mL (840044C-50mg)

enviado en

dry ice

temp. de almacenamiento

−20°C

SMILES string

O[C@H]1[C@@H]([C@H](O)[C@H](O)[C@@H](O)[C@@H]1O)OP([O-])(OC[C@@]([H])(COC(CCCCCCCCCCCCCCC)=O)OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)=O.[Na+]

Descripción general

L-α-phosphatidylinositol (Soy) is a naturally occurring, negatively charged glycerophospholipid with an inositol ring. It is found in biological membranes, which are involved in scaffolding, cellular compartmentalization and signal transduction.

Aplicación

Soy PI has been used in PI 3-kinase assay.

Acciones bioquímicas o fisiológicas

L-α-phosphatidylinositol (Soy) acts as a cellular mediator in signal transduction processes. It is used to design therapeutic delivery vehicles for drug delivery. Soy PI also contributes to the regulation of cholesterol metabolism.

Envase

5 mL Clear Glass Sealed Ampule (840044C-25mg)
5 mL Clear Glass Sealed Ampule (840044C-50mg)
5 mL Clear Glass Sealed Ampule (840044C-10mg)

pictogramas

Skull and crossbonesHealth hazard

Palabra de señalización

Danger

Órganos de actuación

Central nervous system

RIDADR

UN 1888 6.1 / PGIII

WGK Alemania

WGK 3

Punto de inflamabilidad F

does not flash

Punto de inflamabilidad C

does not flash

Vps34 kinase domain dynamics regulate the autophagic PI 3-kinase complex
Stjepanovic G, et al.
Molecular Cell, 67(3), 528-534 (2017)
Phospholipids as cardiovascular therapeutics
Pandey NR and Sparks DL
Current Opinion in Investigational Drugs, 9(3), 281-285 (2008)
Aaron Peng et al.
Chemistry and physics of lipids, 165(1), 15-22 (2011-10-26)
Liposomes consisted of phosphatidylinositol (PI) and phosphatidylcholine (PC) have been utilized as delivery vehicle for drugs and proteins. In the present work, we studied the effect of soy PI on physical properties of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) liposomes such as phase state...
Reorganization of Ternary Lipid Mixtures of Nonphosphorylated Phosphatidylinositol Interacting with Angiomotin
Kimble-Hill, et al.
The Journal of Physical Chemistry B, 122(35), 8404-8415 (2018)
Yoshiko Uchiyama et al.
Brain research, 1151, 46-54 (2007-04-06)
Membrane composition serves to identify intracellular compartments, signal cell death, as well as to alter a cell's electrical and physical properties. Here we use amperometry to show that supplementation with the phospholipids phosphatidylcholine (PC), phosphatidylethanolamine (PE), sphingomyelin (SM), and phosphatidylserine...

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