850340C

Avanti

13:0 PC

1,2-ditridecanoyl-sn-glycero-3-phosphocholine, chloroform

Sinónimos:
PC(13:0/13:0)
Empirical Formula (Hill Notation):
C34H68NO8P
Número de CAS:
Peso molecular:
649.88
NACRES:
NA.25

ensayo

>99% (TLC)

envase

pkg of 1 × 2.5 mL (850340C-25mg)

manufacturer/tradename

Avanti Polar Lipids 850340C

concentración

10 mg/mL (850340C-25mg)

enviado en

dry ice

temp. de almacenamiento

−20°C

Descripción general

13:0 PC is ditridecanoyl phosphatidyl choline (DTPC). Phosphatidylcholine (PC) is a phospholipid, present in endothelial cells, corneal epithelial cells, and fibroblast. Structurally, PC has a polar head consisting of choline and phosphate and two non-polar tails consisting of fatty acids. The polar head group is water soluble and the non-polar tails are water insoluble. Due to its amphiphilic properties, it is present in the cell membrane. In the human body, liver synthesizes PC. Dietary sources of PC are egg and soybeans.
Phosphatidylcholine (PC), a phospholipid carries a positively charged quaternary amine and a negatively charged phosphate in its headgroup. It can form strong bilayer and is an important component of mammalian membranes.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Aplicación

13:0 Phosphatidylcholine (PC) has been used as a lipid standard for mass spectrometry.
13:0 PC (1,2-ditridecanoyl-sn-glycero-3-phosphocholine) may be used as a lipid standard for the quantification of phosphatidylcholines (PCs) by mass spectrometric analysis.

Acciones bioquímicas o fisiológicas

Phosphatidylcholine (PC) can serve as a surfactant in the mucus.
Phosphatidylcholine (PC) is the precursor for the triacylglycerol synthesis. The concentration of PC decreases owing to enhanced triacylglycerol production in the liver. Phosphatidylcholine may be a biomarker for the diagnosis of fatty liver. Its structure enables them to be used in food industry as emulsifiers.

Envase

5 mL Clear Glass Sealed Ampule (850340C-25mg)

pictogramas

Skull and crossbonesHealth hazard

Palabra de señalización

Danger

Órganos de actuación

Central nervous system

RIDADR

UN 1888 6.1 / PGIII

WGK Alemania

WGK 3

Punto de inflamabilidad F

does not flash

Punto de inflamabilidad C

does not flash

Genea Edwards et al.
Biochimie, 101, 232-247 (2014-02-25)
To compare phospholipid (phosphatidylcholine, phosphatidylserine, phosphatidylethanolamine and phosphatidylinositol) profiles of human control and glaucomatous aqueous humor (AQH). AQH samples were procured during surgery from human POAG and control subjects (n = 15 each). Samples were used following institutional review board...
Phospholipid makeup of the breast adipose tissue is impacted by obesity and mammary cancer in the mouse: Results of a pilot study
Margolis M, et al.
Biochimie, 108(11), 133-139 (2015)
Membrane lipids:phospholipids
General, Organic, and Biological Chemistry, 108(11), 581-581 (2006)
Mass spectrometric analyses of phosphatidylcholines in alkali-exposed corneal tissue
Crane AM, et al.
Investigative Ophthalmology & Visual Science, 53(11), 7122-7130 (2012)
Self-assembled phospholipid unilamellar vesicles
Liposomes, Part G (2009)

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