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07-1473
Anti-Phosphothreonine-Proline Antibody
from rabbit, purified by affinity chromatography
All Photos(1)
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
origen biológico
rabbit
Nivel de calidad
forma del anticuerpo
affinity isolated antibody
antibody product type
primary antibodies
clon
polyclonal
purificado por
affinity chromatography
species reactivity
mouse, rat, human
technique(s)
western blot: suitable
enviado en
wet ice
Descripción general
Phosphothreonine-Proline, along with similar motifs involving serine/threonine residues preceding proline undergoing phosphorylation, has critical roles in the moderation of various cellular processes, protein function, and kinases through proline-directed phosphorylation. The deregulation of proline-directed phosphorylation is known to be a factor in diseases such as cancer and Alzheimer’s neurodegeneration.
Especificidad
Recognizes the phosphorylated phothreonine-proline motif, which is the site of phosphorylation of many proline-directed protein kinase such MAPK and cyclin-dependent protein kinases. Also recognizes the phosphoserine-proline motif to a similar degree.
Inmunógeno
KLH-phosphothreonine-proline amide
(pT-P-NH2) peptide conjugates
(pT-P-NH2) peptide conjugates
Aplicación
Detect Phosphothreonine-Proline using this Anti-Phosphothreonine-Proline Antibody validated for use in WB.
Calidad
Evaluated by Western Blot in Calyculin treated Jurkat cell lysate.
Western Blot Analysis: 1:500 dilution of this lot detected phosphorylated proteins on 10 μg of calyculin treated Jurkat lysates.
Western Blot Analysis: 1:500 dilution of this lot detected phosphorylated proteins on 10 μg of calyculin treated Jurkat lysates.
Ligadura / enlace
Replaces: AB3192
Forma física
Liquid in TBS with 0.05% sodium azide and 50% glycerol.
Almacenamiento y estabilidad
Maintain at -20°C in undiluted aliquots for up to 12 months from date of receipt.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
Nota de análisis
Control
Calyculin treated Jurkat cell lysate
Calyculin treated Jurkat cell lysate
Otras notas
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Código de clase de almacenamiento
12 - Non Combustible Liquids
WGK
nwg
Punto de inflamabilidad F
Not applicable
Punto de inflamabilidad C
Not applicable
Certificate of Analysis
Enter Lot Number to search for Certificate of Analysis (COA).
Certificate of Quality
Enter Lot Number to search for Certificate of Quality (COQ).
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