Merck
All Photos(3)

1.02735

SAFC

L-Cysteine hydrochloride monohydrate

EMPROVE® EXPERT, Ph. Eur., JP, USP

Synonym(s):
Cys, L-Cysteinium Chloride Monohydrate, L-Cysteine Hydrochloride, Monohydrate
Linear Formula:
HSCH2CH(NH2)COOH · HCl · H2O
CAS Number:
Molecular Weight:
175.63
Beilstein:
5158059
Número MDL:
Número índice de la CE:
200-157-7

Agency

JP
Ph. Eur.
USP

Nivel de calidad

500

presión de vapor

<0.1 hPa ( 20 °C)

Línea del producto

EMPROVE® EXPERT

ensayo

98.5-101.0% dry basis (alkalimetric)

formulario

crystalline powder

pH

0.8-1.2 (20 °C, 100 g/L in H2O)

mp

168-170 °C

solubilidad

650 g/L

densidad

1.54 g/cm3

densidad aparente

780 kg/m3

trazas de anión

sulfate (SO42-): ≤300 ppm

trazas de catión

Fe: ≤20 ppm
heavy metals (as Pb): ≤10 ppm

temp. de almacenamiento

2-30°C

SMILES string

O.Cl.N[C@@H](CS)C(O)=O

InChI

1S/C3H7NO2S.ClH.H2O/c4-2(1-7)3(5)6;;/h2,7H,1,4H2,(H,5,6);1H;1H2/t2-;;/m0../s1

InChI key

QIJRTFXNRTXDIP-JIZZDEOASA-N

Looking for similar products? Visit Product Comparison Guide

Envase

1 kg in PE bottle
3 kg in Fibre case
10 kg in Plastic drum
25 kg in PE drum

Acciones bioquímicas o fisiológicas

NMDA glutamatergic receptor antagonist.

Nota de análisis

Assay (alkalimetric, calculated on dried substance): 98.5 - 101.0 %
Identity (IR-spectrum): passes test
Identity (Chloride): passes test
Appearance: white to almost white crystalline powder or colorless crystals
Appearance of solution (25 g/l, water): clear and not more intense in color than reference solution BY₆
Spec. rotation (α 20/D, 80 g/l, hydrochloric acid 250 g/l, calc. on dried substance): +5.5 to +7.0
Spec. rotation (α 25/D, 80 g/l, hydrochloric acid 6 mol/l, calc. on dried substance): +5.7 to +6.8
Sulfate (SO₄): ≤ 300 ppm
Heavy metals (as Pb): ≤ 10 ppm
Fe (Iron): ≤ 20 ppm
Related Compounds, total (TLC): ≤ 0.5 %
Ninhydrin-positive substances (LC)(impurity A (570 nm)): ≤ 0.5 %
Ninhydrin-positive substances (LC)(any ninhydrin-positive impurity): ≤ 0.2 %
Ninhydrin-positive substances (LC) (ammonium (570 nm)): ≤ 0.02 %
Ninhydrin-positive substances (LC)(total impurities): ≤ 1.0 %
Residual solvents (ICH Q3C): excluded by manufacturing proces
Sulfated ash (600 °C): ≤ 0.1 %
Loss on drying (Vacuum < 0.7 kPa, P₂O₅, 24 h): 8.0 - 12.0 %
Bacterial endotoxins: ≤ 6.0 I.U./g
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph. Eur., USP.

Información legal

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 1

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

What is the Emprove® Program?

The Emprove® Program is a system providing comprehensive and thorough documentation of our filters and single-use components, pharma raw materials, and starting materials.

Material Qualification Dossier

Free of charge - Sign in to download

Quality Management Dossier

Available by subscription or for a fee

Operational Excellence Dossier

Available by subscription or for a fee

Learn more about the benefits an Emprove® Program subscription can provide
Why are these documents unavailable?
Emprove® Dossiers contain information intended to support the registration process and risk assessment activities of pharmaceutical producers and contain confidential information. Please contact us if you would like access.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service