1.06323

Sodium hydrogen carbonate

EMPROVE^® ESSENTIAL, Ph. Eur., BP, JP, USP, FCC, E 500

• Synonym(s): Sodium bicarbonate
• Linear Formula: NaHCO₃
• CAS Number: 144-55-8
• Molecular Weight: 84.01
• Beilstein: 4153970
• Número MDL: MFCD00003528
• Número E: E500
• Número índice de la CE: 205-633-8

Properties

• Agency: BP; JP; Ph. Eur.; USP
• Nivel de calidad: 500
• reg. compliance: FCC
• Línea del producto: EMPROVE^® ESSENTIAL
• formulario: solid
• pH: 8.6 (20 °C, 50 g/L in H₂O)
• pKa (25 °C): (1) 6.37, (2) 10.25 (carbonic acid)
• mp: 270 °C (decomposition)
• solubilidad: 96 g/L
• densidad: 2.22 g/cm³ at 20 °C; 2.16 g/mL at 25 °C (lit.)
• application(s): liquid formulation; ophthalmics; pharmaceutical; solid formulation
• temp. de almacenamiento: 2-30°C
• SMILES string: [Na+].OC([O-])=O
• InChI: 1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1
• InChI key: UIIMBOGNXHQVGW-UHFFFAOYSA-M

Description

Descripción general

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Aplicación

Sodium hydrogen carbonate is a commonly used ingredient in both food and pharmaceutics. In pharmaceutical applications, sodium hydrogen carbonate is used as pH adjuster, or a source of carbon dioxide in oral formulations such as effervescent tablets or granules.

Información legal

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Código de clase de almacenamiento: 13 - Non Combustible Solids
• WGK: WGK 1
• Punto de inflamabilidad F: Not applicable
• Punto de inflamabilidad C: Not applicable