Merck
  • 119135
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119135

Sigma-Aldrich

Adenosine A1 Receptor Agonist I, CPA

Synonym(s):
Adenosine A1 Receptor Agonist I, CPA
Empirical Formula (Hill Notation):
C15H21N5O4
CAS Number:
Molecular Weight:
335.36
Número MDL:

Análisis

≥99% (HPLC)

Nivel de calidad

formulario

solid

potencia

0.8 nM Ki

manufacturer/tradename

Calbiochem®

condiciones de almacenamiento

OK to freeze
protect from light

color

white

solubilidad

1 M HCl: 100 mM
DMSO: 100 mM
ethanol: 25 mM

enviado en

ambient

temp. de almacenamiento

2-8°C

InChI

1S/C15H21N5O4/c21-5-9-11(22)12(23)15(24-9)20-7-18-10-13(16-6-17-14(10)20)19-8-3-1-2-4-8/h6-9,11-12,15,21-23H,1-5H2,(H,16,17,19)/t9-,11-,12-,15?/m1/s1

InChI key

SQMWSBKSHWARHU-FJFSNTMWSA-N

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This Item
119136119149119139
assay

≥99% (HPLC)

assay

≥99% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

solid

form

solid

form

powder

form

solid

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

storage condition

OK to freeze, protect from light

storage condition

OK to freeze, protect from light

storage condition

OK to freeze, protect from light

color

white

color

white

color

white

color

white

solubility

1 M HCl: 100 mM, DMSO: 100 mM, ethanol: 25 mM

solubility

DMSO: 100 mM, water: 5 mM

solubility

DMSO: 15 mg/mL

solubility

DMSO: 20 mg/mL

Descripción general

A potent and selective agonist of adenosine A1 receptor (A1R) (Ki = 2.3 nM, 790 nM, 18.6 µM, 43nM for human A1, A2A, A2B, and A3, respectively).

Acciones bioquímicas o fisiológicas

Primary Target
A1
Reversible: yes

Advertencia

Toxicity: Standard Handling (A)

Nota de preparación

slight warming is required for complete solubilization in ethanol

Reconstitución

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Otras notas

Migita, H., et al. 2008. J Neurosci Res.86, 2820.
Burgdorf, C. et al. 2005. J Cardiovasc Pharmacol.45, 1.
Klotz, K. N., et al. 2000. Naunyn Schmiedebergs Arch Pharmacol. 362, 382.
Mironov, S., et al. 1990. J Neurophysiol.81, 1.
Monopoli, A., et al. 1994. Arzneimittelforschung.44, 1305.
Concas, A., et al. 1993. J Pharmacol Exp Ther.267, 844.
Lohse, M. J., et al. 1988. Nauryn Schmiedebergs Arch Pharmacol.337, 687.
Coffin, V. L., et al. 1987. J Pharmacol Exp Ther.241, 76.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable


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