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264103

Millipore

Deoxycholic Acid, Sodium Salt, ULTROL® Grade

Highly purified and intended for use as a detergent to solubilize membrane-bound proteins in their native state.

Sinónimos:
Desoxycholic acid sodium salt, 3α,12α-Dihydroxy-5β-cholanic acid sodium salt, Sodium deoxycholate, 7-Deoxycholic acid sodium salt
Empirical Formula (Hill Notation):
C24H39NaO4
Número de CAS:
Peso molecular:
414.55
Beilstein:
3581950
Número MDL:

Nivel de calidad

100

ensayo

≥99% (TLC)

formulario

solid

mol peso

micellar avg mol wt 1200-5000
micellar wt 1200-4900

manufacturer/tradename

Calbiochem®

condiciones de almacenamiento

OK to freeze
desiccated (hygroscopic)

número de agregación

3 - 12
3-12

color

white

pKa 

6.2

CMC

2 - 6 mM
2-6 mM (20-25°C)

HLB

16

enviado en

ambient

temp. de almacenamiento

15-25°C

SMILES string

[Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2

InChI

1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1

InChI key

FHHPUSMSKHSNKW-SMOYURAASA-M

Descripción general

Absorbance (10%, H2O, 290 nm):≤0.25.
Highly purified and intended for use as a detergent to solubilize membrane-bound proteins in their native state (absorbance: <0.25 at 290 nm, 10% H2O; aggregation number: 3-12; CMC: 2-6 mM; micellar weight: 1200-4900; pKa: 6.2). Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 µM).
Highly purified and intended for use as a detergent to solubilize membrane-bound proteins in their native state. Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 µM). Aggregation number: 3-12.

Envase

5, 25 g in Glass bottle

Advertencia

Toxicity: Harmful (C)

Nota de preparación

Do not use with Mn2+ in solution.

Reconstitución

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C. Discard if bacterial or fungal growth is observed.

Otras notas

Pai, R., et al. Mol. Biol. Cell15, 2156.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
ULTROL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictogramas

Exclamation mark

Palabra de señalización

Warning

Frases de peligro

Clasificaciones de peligro

Acute Tox. 4 Oral

Código de clase de almacenamiento

13 - Non Combustible Solids

WGK

WGK 1

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificado de Análisis

Certificado de origen

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