472804

Millipore

S-Methyl-L-thiocitrulline, Dihydrochloride - CAS 209589-59-3 - Calbiochem

A cell-permeable inhibitor of nitric oxide synthase that exhibits about 17-fold greater selectivity for rat neuronal nitric oxide synthase (IC₅₀ = 300 nM) compared to the endothelial enzyme (IC₅₀ = 5.4 µM).

Sinónimos:
Nδ-(S-Methyl)isothioureido-L-ornithine, S-Methyl-L-thiocitrulline, Dihydrochloride - CAS 209589-59-3 - Calbiochem, N δ-(S-Methyl)isothioureido-L-ornithine
Empirical Formula (Hill Notation):
C7H15N3O2S · 2HCl
Número de CAS:
Peso molecular:
278.20

storage conditions

+2C to +8C

Nivel de calidad

100

ensayo

≥95% (HPLC)

formulario

solid

manufacturer/tradename

Calbiochem®

condiciones de almacenamiento

OK to freeze
desiccated (hygroscopic)

color

white to off-white

solubilidad

water: 50 mg/mL

enviado en

ambient

temp. de almacenamiento

2-8°C

InChI

1S/C7H15N3O2S/c1-13-7(9)10-4-2-3-5(8)6(11)12/h5H,2-4,8H2,1H3,(H2,9,10)(H,11,12)/t5-/m0/s1

InChI key

NGVMVBQRKZPFLB-YFKPBYRVSA-N

Descripción general

A cell-permeable inhibitor of nitric oxide synthase that exhibits about 17-fold greater selectivity for rat neuronal nitric oxide synthase (IC50 = 300 nM) compared to the endothelial enzyme (IC50 = 5.4 µM).
A cell-permeable, inhibitor of nitric oxide synthase that exhibits about 17-fold greater selectivity for rat neuronal nitric oxide synthase (IC50 = 300 nM) compared to the endothelial enzyme (IC50 = 5.4 µM).

Envase

10 mg in Plastic ampoule
Packaged under inert gas

Acciones bioquímicas o fisiológicas

Cell permeable: yes
Primary Target
Rat neuronal nitric oxide synthase
Product does not compete with ATP.
Reversible: no
Target IC50: 300 nM for rat neuronal nitric oxide synthase

Advertencia

Toxicity: Standard Handling (A)

Otras notas

Krishnaswamy, N., et al. 1995. J. Biol. Chem.270, 11103.
Furfine, E.S., et al. 1994. J. Biol. Chem. 269, 26677.
Narayanan, K., and Griffith, O.W. 1994. J. Med. Chem.37, 885.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

storage_class_code

11 - Combustible Solids

WGK Alemania

WGK 3

Certificado de Análisis

Certificado de origen

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