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8.51013

Sigma-Aldrich

HATU

Novabiochem®

Sinónimos:
HATU
Empirical Formula (Hill Notation):
C10H15N6O · F6P
Número de CAS:
Peso molecular:
380.23
Número MDL:

Nivel de calidad

300

línea de producto

Novabiochem®

reaction suitability

reaction type: Coupling Reactions

manufacturer/tradename

Novabiochem®

mp

186 °C (decomposes)

temp. de almacenamiento

2-8°C

InChI

1S/C10H15N6O/c1-14(2)10(15(3)4)17-16-9-8(12-13-16)6-5-7-11-9/h5-7H,1-4H3/q+1

InChI key

WXIONIWNXBAHRU-UHFFFAOYSA-N

Descripción general

A highly efficient coupling reagent for solid and solution phase peptide synthesis. In comparative studies HATU has been found to give better coupling yields with less enantiomerization that HBTU, TBTU or PyBOP® [1-3]. It is particularly effective at coupling to N-alkyl amines where other coupling reagents give poor yields and is the preferred reagent for loading resins bearing secondary amino groups.

The product number for this product was previously 01-62-0041.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

Ligadura / enlace

Replaces: 01-62-0041

Información legal

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
PyBOP is a registered trademark of Merck KGaA, Darmstadt, Germany

Certificado de Análisis

Certificado de origen

Artículos

Peptide Coupling Reagents Selection Guide

Novabiochem® offers a large number of coupling reagents for in situ activation. In situ activating reagents are easy to use, fast reacting – even with sterically hindered amino acids, and their use is generally free of side reactions.

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