Histone-lysine N-methyltransferase SUV39H2 is also called Histone H3-K9 methyltransferase 2 (H3-K9-HMTase 2), Lysine N-methyltransferase 1B, and Suppressor of variegation 3-9 homolog 2 (Su(var)3-9 homolog 2). Histone-lysine N-methyltransferase SUV39H2 is a histone methyltransferase that specifically trimethylates ′Lys-9′ of histone H3 using monomethylated H3 ′Lys-9′ as substrate, which creates a specific tag for epigenetic transcriptional repression and directs DNA methylation at pericentric repeats. Histone-lysine N-methyltransferase SUV39H2 is involved in several processes, including cell cycle regulation, transcriptional repression, regulation of telomere length, and higher-order chromatin organization during spermatogenesis.
KLH-conjugated linear peptide corresponding to human Histone-lys N-methyltransferase SUV39H2.
Immunoprecipitation Analysis: 10 µg from a representative lot detected Histone-lys N-methyltransferase SUV39H2 in 500 µg of MDA-MB-435 cell lysate.
Epigenetics & Nuclear Function
Research Sub Category
Detect SUV39H1 using this rabbit polyclonal antibody, Anti-Histone-lysine N-methyltransferase SUV39H2 Antibody validated for use in western blotting & IP.
Evaluated by Western Blotting in human testis tissue lysate.
Western Blotting Analysis: 2 µg/mL of this antibody detected Histone-lys N-methyltransferase SUV39H2 in 10 µg of human testis tissue lysate.
Descripción de destino
~51 kDa observed. Uncharacterized band(s) may be observed in some cell lysates.
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Almacenamiento y estabilidad
Stable for 1 year at 2-8°C from date of receipt.
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.