Merck
  • ABE559
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ABE559

Sigma-Aldrich

Anti-Xrcc1 Antibody

serum, from rabbit

Synonym(s):
DNA repair protein XRCC1, X-ray repair cross-complementing protein 1
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

forma del anticuerpo

serum

antibody product type

primary antibodies

clon

polyclonal

species reactivity

mouse, human, rat

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

Nº de acceso NCBI

Nº de acceso UniProt

enviado en

wet ice

Gene Information

human ... XRCC1(7515)

Descripción general

DNA repair protein XRCC1 (X-ray repair cross-complementing protein 1) is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. XRCC1 interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells.

Inmunógeno

Linear peptide corresponding to mouse Xrcc1.

Envase

100 μL

Aplicación

Anti-Xrcc1 Antibody is a highly specific rabbit polyclonal antibody, that targets XRCC1 & has been tested in western blotting & IP.
Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected Xrcc1 in HepG2 cell lysate.

Western Blotting Analysis: A representative lot from an independent laboratory detected Xrcc1 in HEK293T, HeLa and MEF cell lysates (Lee, Y., et al. (2009). Nature Neurosci. 12:(8):973-980.).

Immunoprecipitation Analysis: A representative lot from an independent laboratory detected Xrcc1 in HEK293T, HeLa and MEF cell lysates (Lee, Y., et al. (2009). Nature Neurosci. 12:(8):973-980.).

Calidad

Evaluated by Western Blotting in Jurkat cell lysate.

Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected Xrcc1 in 10 µg of Jurkat cell lysate.

Descripción de destino

~80 kDa observed. The molecular weight of this protein is calculated at 69 kDa; however it has been observed at ~80 kDa (Lee, Y., et al. (2009). Nature Neurosci. 12:(8):973-980.). An uncharacterized band may be observed at ~51 kDa in some cell lysates.

Código de clase de almacenamiento

10 - Combustible liquids

WGK

WGK 1

Certificate of Analysis

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Certificate of Quality

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