ABE603

Sigma-Aldrich

Anti-GLE1 Antibody

from rabbit, purified by affinity chromatography

Sinónimos:
Nucleoporin GLE1, hGLE1, GLE1-like protein
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

100

antibody product type

primary antibodies

clon

polyclonal

purificado por

affinity chromatography

species reactivity

mouse

species reactivity (predicted by homology)

human (immunogen homology)

aplicaciones

immunohistochemistry: suitable
western blot: suitable

Nº de acceso UniProt

enviado en

wet ice

Descripción general

Nucleoporin GLE1 or GLE1-like protein (GLE1L) is an mRNA export factor in both human and yeast cells and interacts with nuclear pore complex proteins NUP155 and NUPL2. GLE1 may act at a terminal step in the export of mature RNA messages to the cytoplasm. Mutations in GLE1 have been associated with lethal congenital contracture syndrome type 1 (LCCS1) and lethal arthrogryposis with anterior horn cell disease (LAAHD).

Especificidad

This antibody recognizes the C-terminus of GLE1.

Inmunógeno

KLH-conjugated linear peptide corresponding to the C-terminus of human GLE1.
Epitope: C-terminus

Aplicación

Research Sub Category
Transcription Factors
Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected GLE1 in mouse brain tissue.
Detect Nucleoporin GLE1 using this rabbit polyclonal antibody, Anti-GLE1 Antibody validated for use in western blotting & IHC.
Research Category
Epigenetics & Nuclear Function

Calidad

Evaluated by Western Blotting in mouse brain tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected GLE1 in 15 µg of mouse brain tissue lysate.

Descripción de destino

~93 kDa observed. Uniprot describes 2 isoforms at ~75 kDa and ~80 kDa Uncharacterized bands may appear in some lysate(s).

Forma física

Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Nota de análisis

Control
Mouse brain tissue lysate

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK Alemania

WGK 1

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico

Redes sociales

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

Merck

Investigación. Desarrollo. Producción.

Somos un proveedor líder para la industria de Ciencias de la Vida con soluciones y servicios para investigación, desarrollo y producción biotecnológicos, y para desarrollo y producción de tratamientos farmacéuticos

© 2021 Merck KGaA, Darmstadt, Alemania y/o sus filiales. Todos los derechos reservados.

Queda estrictamente prohibida la reproducción sin permiso de cualquiera de los materiales de la página web.